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Age Spots: What They Are And What They Mean
152 Plays4 months ago
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Transcript
00:00:01
chrisyzen
Hey, it's Christian Jardinoff. So yesterday in the May, I got this anti-aging pharmaceutical that i I buy and the company that sends it, they send you a little gift every time and it's usually a bunch of crap that just gets thrown out. But this time, along with like some melatonin gummies with a bunch of crappy ingredients and a sucker and some weird skin wipe there was this anti-pigment cream for serum, dual serum hyperpigmentation anti-pigment dual serum with patented thiamidol from usurin which is i think you probably know that company so i thought let me
00:00:52
chrisyzen
It kind of reminded me that I've wanted to do ah an episode on age pigment or age spots, what they are, why do we get them and so on. So um it kind of inspired me. So I looked up the this ingredient thiamidyl, thiamidyl, and basically it is
00:01:15
chrisyzen
it It works by inhibiting the enzyme tyrosinase, which is a key enzyme in the production of melanin, which is the pigment responsible for skin color. So it stops the production of melanin locally when you apply it by inhibiting that enzyme tyrosinase. But do we really want that? Is that the way to reduce skin pigmentation when actually this disturbed production of melanin causes things like vitiligo, like that you know that skin disease where the person loses pigmentation in their skin?
00:01:57
chrisyzen
um so this is kind of we're using similar mechanism so it's a very it's a very allopathic way of trying to you know undo the damage of the liver spots but here's here's the thing that we have to understand this is so critical to understand if you have liver spots on your skin this is actually super commonology you can go on wikipedia right now or chat gpt
00:02:30
chrisyzen
and and and type in lipo fuskin ah fuin lipo f u c if sorry f u s c i lipo fusin or fuskin That is the name given to the yellow the fine yellow brown pigment granules composed of lipid containing residues of lysosomal degradation. And here's the thing, it is considered to be one of the aging or wear and tear pigments found in the liver, the kidney, heart muscle, retina,
00:03:08
chrisyzen
adrenals, nerve cells and other places. So point being, if you have liver spots on your skin, the skin health is a window into the body's overall health. So you if you see the stuff in your skin, it's in your body, right? And this chemical-laden garbage cream, anti-pigment duosirium with the 30 chemicals in there. What's interesting is that the second chemical in the list is actually denatured alcohol. And from what I understand is that ethanol or alcohol can help to dissolve some of this H pigment. So I wonder,
00:03:53
chrisyzen
Could that actually be the active the more active ingredient in there? Or could that be producing much of the effect um as well? So it the on the one hand, the chemical is inhibiting that enzyme tyrosinase involved in the melon ah melanin production. And then on the other hand, the alcohol is actually helping to dissolve some of the sage pigment. right But in whatever whatever the mechanism of action is, This is way, way, way more serious of an issue than just look our skin looking a little bit better. Because again, if we have this these liver spots on our skin, it means we have them in our organs, right? In our heart, kidneys, liver, and um ah retina, adrenal glands, nerve cells, right?
00:04:46
chrisyzen
So we need we need to preempt but this kind of stuff while we are still relatively young and healthy before a lot of the stuff starts forming and becomes visible on our skin. Because again, by the time it's visible on your skin, it means a lot of damage. like ah Like I always say, by the time you feel a symptom, whatever that is, a headache or whatever else, it generally means that a lot of dysfunction and damage has been occurring deeper in the body and this is a big part of my longevity philosophy and methodology is we want to preempt these things these imbalances in the body before they cause us the visible or noticeable or palpable issues okay so
00:05:37
chrisyzen
here's the the part that may blow you away what is how is lipophasket or how is this H pigment actually created this when you understand this you will start to understand why i am so not militant i don't like that word but why i keep harping on if you especially if you're a client why i keep harping on about getting these doggone omega-6's poof as well and such a fat out of the the diet as much as possible even if that means we don't eat out as much or we have to make some serious changes about what we order when we go out um but also not just that but you will probably understand why i do not i no longer recommend omega-3
00:06:32
chrisyzen
supplementation. So here is the step here are the steps in how this H pigment lipophoskin forms. So you need some kind of oxidative stress and cellular damage. So you can have obviously a lot of different reactive oxygen species in the cells and so on that some of them ah are formed as part of our energy metabolism. So we can't really escape them. um truly we can't but you can also have other ways if you have let's say a lot of this stuff in your tissues this um when i say this stuff i mean a lot of these omega sixes and omega threes a lot of these polyunsaturated fats
00:07:19
chrisyzen
And then you're exposed to the stress of the UV radiation of the sun. That is another way for these polyunsaturated fats to get damaged, which will cause this chain reaction of of damage that can end and in the the formation of this H pigment, this lipophasket. So lipid peroxidation of the polyunsaturated fats let's say they're in the mitochondria or in the cell membranes or whatever, this causes the formation of secondary products like MDA, melanaldehyde for hydroxy, non-anal
00:08:05
chrisyzen
These, so the reactive oxygen species and these lipid peroxidation byproducts, they can modify proteins leading to basically to damage. And then there's this cross-linking between like sugars and lipids. But again, this needs you need to have polyunsaturated fats for this really too to become an issue for a human. And then some of some of ah there's some aspect of like um a mineral or a metal like iron, copper, and zinc reacting with this. So a lot of this lipophoskin, just to kind of make a long story short, a lot of this lipophoskin is polyunsaturated fats and some kind of metals. All right, so iron.
00:08:56
chrisyzen
zinc, copper, and perhaps perhaps even you know aluminum and toxic metals. right But here is the the part that is kind of what people need to understand. If you ask Chad GPT, my new favorite assistant,
00:09:18
chrisyzen
ah So I asked it, which polyunsaturated fats are most implicated in lipofascin formation? It is clearly common knowledge, well not common knowledge, but it's clearly well established in the scientific literature that um the PUFAs most implicated in lipofascin formation include omega-3 fatty acids. So Ecosopentanoic acid, EPA, the cosohexanoic acid, DHA. So the two the two omega-3s that are sold as the answer to all of our problems, super super highly anti-inflammatory and heart health and good for the brain and all that jazz. These, especially DHA, these are actually even more fragile
00:10:10
chrisyzen
than omega sixes because they're more polyunsaturated so omega sixes are polyunsaturated but omega threes are even more polyunsaturated so yes linoleic and arachidonic acid the omega sixes are implicated in lipophosic information but if you have a lot of omega threes in your tissues that is an even bigger risk for this lipophosic information especially When in an in an ideal world, let's say you live in a cold environment and you're not stressed, maybe things won't be so bad. But if you're under a lot of stress yeah and you you know your diet is suboptimal, you don't supplement, your antioxidant status is poor, and then you go out in the sun, the UV damage or the uv light from the sun
00:11:01
chrisyzen
damages these polyunsaturated fats in your skin and that chain reaction then of damage of lipid peroxidation byproducts and all that stuff. At first, you know you can deal with it when you're younger, when your you know your antioxidant status is better, you better ah the body's better at making trade-offs so it can rub Peter to pay Paul as it were. So if there's a lot of this kind of damage going on, it will, the body will halt other less vital for survival functions in order to divert nutrients, resources, et cetera, to mitigating, ameliorating some of the damage caused by this. But over time, that's why they're also called age spots is because over time, as we age and accumulate a lot of damage, we are less able to, to do these kinds of things and, you know,
00:11:55
chrisyzen
but Repair damage protect from damage and so on and so forth um so That is why I do not recommend Omega 3s anymore. That's why last year, I guess around this time last year, I started, you know, understanding some of the stuff and I very quickly got my clients off of the... no not not I didn't even have all my clients at the time on Omega 3s.
00:12:29
chrisyzen
but the ones that were on Omega 3s at first i I just told most of them just put it in the fridge and pause it for a while and um time time went by I did more research and I'm gonna probably have a whole chapter on this why I don't recommend Omega 3s anymore in in the next volume of the How to Actually Live Longer series Um, and um'm I'm going to do like an episode probably on it here, but, um,
00:13:05
chrisyzen
it, it was not, it was not easy because look, if you, if you go on, like I have this, uh, book, um, series, it's a two volume set. Um, the textbook of natural medicine, 2000 pages on $250, uh, uh, book set, uh, fifth edition and. the chapter on omega-3 supplementation. the If you read that, you'd be like, oh my God, this is the best thing since sliced cheese, right? And if you look at the amount of research that is being produced on how you know good omega-3s are, it kind of
00:13:47
chrisyzen
it will be very difficult to to accept this and I don't expect you to listen to you know a 20-minute episode and accept it because i I myself why haven't I done an episode on it yet fully is because I haven't read all the research that I've collated haven't delved into it super deep but um I
00:14:13
chrisyzen
And I was pretty big, no I wasn't big into omega-3 supplementation ah as such, but I was big into getting omega-3s through the diet, you know, so cans of cod liver and fish, what's it, hake row. I'd get that in cans and we would eat fish more often. I kind of stopped all of that really. um I still have lots of cans of cod liver, um which by the way, cod liver and ah and fish eggs, there's a lot of protein in there. There's a lot of other minerals and vitamins and you know vitamin A and so on. So it's not all omega threes. So, you know, getting eating fish is
00:15:04
chrisyzen
It's OK. I'm not saying don't eat fish or whatever. Don't eat any Omega 3. It's probably impossible to eat to not eat any Omega 3s or Omega 6s for that matter. It's almost impossible to have a 0x diet in anything because even fruit has protein. um you know's It's impossible to exclude a specific food group or subsection of a food group. But my point is here.
00:15:33
chrisyzen
We. given how prone even if these things are genuinely good for us and genuinely essential the Omega 3s and Omega 6s first of all they're they're needing tiny tiny amounts but even if they are beneficial and whatever else in essential they are still extremely prone to this lipid peroxidation process so my personal
00:16:04
chrisyzen
strategy for longevity and health and restoring health, if one were to need that sort of thing, would be to be extremely avoidant of polyunsaturated fats for a lengthy period of time. And as you can see, because ah omega-3s are even more prone to lipid peroxidation, having a lot of them in our tissues, and that that that's beyond just the skin, as I mentioned already, in our liver, in our brain, other organs, et cetera. Having more of those means we have more of a risk for this lipophoskin to form, right? And at the end of the day,
00:16:58
chrisyzen
If we have liver spots, age spots, ah those those are probably the least of our problems on on in the grand scheme of things, if especially if the stuff is in our brain and our liver. so but which kind of also goes the so the other the other thing that's interesting is they're called liver spots some people call them liver spots why do you think that that is excuse me why do you think that is well as it turns out the skin is also a detoxification organ so the more congested a person's liver is
00:17:39
chrisyzen
the more the body is inclined to use other routes of detoxification that are available to it. So this is, I believe, another reason why we get, um some people get these more than others. For example, I'll tell you this homeopath we went to a couple of years ago, he was 80, this German dude tall, his skin was perfect, 80 years old, his skin was friggin perfect. And the so that's a person that obviously knows a thing or two about health, if we're going to see him for health advice. um So
00:18:24
chrisyzen
You can, you the this is, these liver spots or age spots are not a feature of aging. They're more a feature of the modern diet, the modern lifestyle. the the depleted human of this 21st century, so they're more ah kind of a feature of this modern world than an actual feature of aging that is inevitable. but A lot of these, like I talk about in my How to Actually Live Longer book,
00:18:57
chrisyzen
A lot of these features quote on quote of aging like oxidative stress, increased inflammation, yeah even things like osteopenia, osteoporosis, a lot of these things are they're not features They're not even features. they're If you know the information that I know and teach my clients and have in my books and we're having future books and so on, if you know that information, then these things, these quote unquote features become optional extras that you can choose to avoid by doing actually at the end of the day, very simple things. And they're not even too expensive. They're not even expensive when you consider it the other option of
00:19:41
chrisyzen
you know having a horrible ah lifestyle and health and ah you know just the last 10, 15, 20 years of your life being ah the slow horrible painful degeneration, this torture that like, for example, my grandmother went through, you know, and then going to the doctors and them just giving you more poisons and then making everything worse. And until it all ends in a hospital bed where you're, you know, drugged and can't even be around your family, whatever. That's how she died during the Covid times, you know. So.
00:20:22
chrisyzen
that's That's the other option. So when someone says, you know, of a few thousand bucks for to work with a health care butt or health practitioner or whatever, a couple hundred bucks per month on supplementation, it's too much money or it's wasted money and it's like, really? ah like go Go look at some old folks in in their 70s, 80s, see how they're doing, not doing any of the stuff, and then see look at your options. what do you know what the The problem is we don't really think about these we don't think about the future. Most people don't don't tend to think about the future, what things will be like, and especially men, we don't really do that.
00:21:05
chrisyzen
And for me, the only the only reason I kind of do this stuff now is because and in my 20s, I lived like really poorly, ah really unhealthily. And then I saw my granny kind of
00:21:23
chrisyzen
slowly degenerate I saw the torture it was for her and then for you know her daughters my mom my ah my aunt and their you know the extended family I saw how torturous of a life that is to be so incapacitated when you can't even take care of yourself anymore. And that's that was the wake up call I needed. And then I just kind of took it to a fairly extreme ah state after that.
00:21:54
chrisyzen
which most people don't even have to do. you know ah my My clients don't do a lot of the stuff I do because this this is not their job. A lot of the stuff I do is because I'm researching new things and new supplements and I kind of have to be lead by example, quote unquote. So if you when you look at I just in the last couple of days I got some fatty acid analysis tests which I'm gonna do a whole episode about that test um but you know I told the clients there were about 40 to 42 percent omega-6s in their in their test so I told them this is not good because even the lab range
00:22:38
chrisyzen
which is done with a lot of American, um for the most part, an American population. So we know ah in America, there's a lot of seed oils in foods everywhere and a lot of people eat out. So a lot of people eating, a lot of people doing those fatty acid analysis tests are gonna have a very high omega-6 content in their in their blood. So, but in spite of that, the range is 26% to 43.5%. So these clients, I told them you were at 40, you were at 42. That's right at the top of the range, right? As an example, I did this test last year around October, November, I think. And my Omega-6s were 10%, just over 10%.
00:23:33
chrisyzen
So we're talking 40% Omega-6s and 10%. And very few people probably or are in that range. So I kind of have to, because this is my job, I have to lead by example, and not everybody needs to be that way. but um
00:23:53
chrisyzen
but it's it's important to start trending in that direction if you want to avoid not if you want to avoid not just this age pigment on the skin but also it again it this stuff if it's on the skin It's in the brain, it's in the organs, the kidneys, the adrenals, and so on, right? And the the biggest sort of lever in how much of this stuff gets produced is the amount of unsaturated fats in the tissues. That includes omega-6 fatty acids and omega-3 fatty acids.
00:24:37
chrisyzen
So there's a lot of the great deal of control you have right there. And then of course, because it takes a very long time, it can take so something like two to four to seven years for um fatty acids in the tissues to actually be replaced. The half-life is like two years. so it can take up to seven years for the stuff to get replaced even if you stop eating Omega-6s today completely or you know within reason let's say you you get it down to like five ten grams a day it will still take years and years for this stuff to get out of your body so in the meantime
00:25:25
chrisyzen
you want to protect those polyunsaturated fats from oxidation, from lipid peroxidation, because that will initiate these cascades that can end up in this lipophascin, this H pigment being created. So in the meantime, your best sort of protection insurance is actually vitamin E. And in my book, How to Actually Live Longer, if you get the book, you can there's a whole chapter on how important getting the seed oils and the not just the seed oils but in general i don't even recommend eating nuts much to be quite honest um because that's where seed oils come from your seeds and nuts
00:26:06
chrisyzen
So vitamin E is a good protection. And if you get the book, you also get the appendix where the, uh, with the products that I use. So this is very, very important because if, even if you, here's the thing, if you completely remove the seeds and the nuts and the, obviously the oils from, from them, from the diet, What happens is very quickly your um um your vitamin E levels will drop because in a weird sort of irony, which isn't so weird, seeds and nuts and seed oils are the best sources of vitamin E. So if you remove the stuff from the diet,
00:26:52
chrisyzen
mean um and you don't supplement vitamin E judiciously over the next four years or so, ah you were leaving a lot of these vulnerable to oxidation, polyunsaturated fats, omega-6s and omega-3s that are in your tissue, you were leaving them vulnerable to this damaging process, this peroxidation. So if you don't supplement vitamin E, you are actually
00:27:24
chrisyzen
You're putting yourself at risk than when you and you get stressed, when you get out in the sun or whatever. um
00:27:34
chrisyzen
this This process can get initiated, you know, the the reactive oxygen species, the lipid peroxidation byproducts, the aldehydes, the malon dialdehyde, then deoxidized proteins and amino acids, the advanced glycation end product, you know, fusing together with the iron. and That's the other thing is our diet in the West, especially if you're eating a processed, a lot of processed food. There's a lot of cereals are fortified with iron. There's a lot of iron everywhere. And that's, that's another big issue in today's world. So the more iron you have in your tissues and your diet, the less your antioxidant status or the lower your antioxidant status, the more of these
00:28:21
chrisyzen
body and saturated fats you have in your body. Very simply, bluntly put, the faster you will age because you will accrue damage faster and there will be things there will be a lot of damaging compounds or easily damaged compounds and not enough of the stuff that helps to ameliorate that damage for example the vitamin E but there's other things involved here obviously it's not just vitamin E but that's a good place to start so yeah I think I'll leave it there the moral of the story I think you understand is we really have to just really take this seriously I think people it's kind of
00:29:01
chrisyzen
Seems like people or in the mainstream not just people and because people are a lot of people just they just go to them the mainstream for their health advice, but the mainstream sort of narrative is that the only problem with the seed oils and the all these Omega-6s is because fat has you know nine calories per gram, there's a potential for to overeat. Let's say if your stir fry had
00:29:34
chrisyzen
let's say 10 grams or 20 of or twenty grams of ah soybean oil, that ah that's, you know, 180 calories or 90 calories extra. So over the years that can lead to weight gain, obesity, and then that can, et cetera, et cetera, diabetes, blah, blah. um that's That's a very sort of dumbed down caricature of the problem. It is a straight up lie that these things are benign. Even if they're okay if if the soybean is used you you know in high heat cooking or frying, so some of them will accept that there are you know these lipid peroxidation byproducts that are dangerous potentially.
00:30:16
chrisyzen
but They're saying if you just eat this stuff, let's say cold pressed, whatever almond oil or whatever else, it's totally fine. but it's actually not totally fine because even if you have the stuff in the fridge it will peroxidize it will go rancid now imagine the stuff is in your tissues and instead of five degrees celsius you're almost 37 degrees celsius right so we are actually very warm beings at least we should be right and unless you have severe hypothyroidism um so these things if they go rancid in the fridge they will go rancid
00:30:56
chrisyzen
in your body. And then of course the body will then do stuff to ameliorate the damage and excrete it and blah, blah, blah. But that is a, it will it's it's better, it's like a pound, an ounce of prevention is worth a pound of cure, that kind of thing. So you're better off not letting that deplete your antioxidants and divert all this crucial energy and all these nutrients, vitamins, minerals, instead of these being diverted to mitigate some of this damage occurring in your body. you're better off not not putting yourself in that position to begin with and then allowing that energy in those nutrients to go to regeneration processes and support higher cognitive function and all the cool stuff you want to do instead of just surviving you could be thriving and a big
00:31:44
chrisyzen
Massive part of that is getting these dog gone Omega sixes and a lot of these, at least the extra Omega threes. My point, my point there is I wouldn't go out of my way to be adding Omega threes into my diet. Like I ah really, I would do a whole episode, like I said, in the whole chapter in the next book. But i would not be I would not be adding omega-3s supplementarily and stuff like that. And I wouldn't be eating fish every day, especially the the cold water fish. Because when you look at just comparing tropical fish to cold water fish,
00:32:33
chrisyzen
tropical fish will have less omega 3s they'll have more saturated fat and then cold water fish like salmon or whatever else they'll have a lot more omega 3s and their nature doesn't make mistakes there's a reason why the cold water organisms have more omega 3s because they they are kind of like an antifreeze. They remain liquid even at very low temperatures. So if you're warm, if you're a tropical type creature, which we are 37 degrees, it's very warm or 36.9, whatever. We're actually very warm. if you You can also look at it this way. ah Palm oil and coconut oil are mostly saturated.
00:33:18
chrisyzen
is because they live in more tropical climates, whereas things that live more north, like some of these nuts and seeds, they have a lot more omega-6s or a lot a lot more polyunsaturated fats. The reason the seed has these polyunsaturated fats is actually to help kind of keep it alive, give it an energy source in the winter when it's underground. under potentially a blanket of snow. So then when the ground thaws and whatever spring comes about, um that little bit of polyunsaturated fat will feed the plant, give it energy to sprout and start growing set roots.
00:34:01
chrisyzen
so the the The reason seeds and nuts have a lot of vitamin E relatively to other foods is because the vitamin E is there to protect those fragile polyunsaturated fats. That's why we extract vitamin E from seeds and nuts from sunflower seeds and soybean and palm ah oil and wheat germ oil and so on. right so But think about it this way. We are warm-blooded organisms. We don't live up in the North, in the Arctic. And we sure we sure as hell can't naturally survive there. We can with technological advances. But nature clearly did not build us to survive those cold climates like a seal or whatever, or ah or a salmon. So we even if they're essential, we need tiny amounts of them. They should be kept out of our diets, out of our bodies for the most part, because
00:35:01
chrisyzen
never mind the age pigments and all this lipofasc information and the newer generation component. like when When you look at like my clients, the ones the people generally that have the most health issues, their Omega-6s on this test that we do are in the like almost 40% range. so How did, how did we get here? You know, how did we, these tropical beings, 30, 36.9 degrees Celsius body temperature, how are we now 40% freaking Omega six is this is not, this is not a normal state of being where this is not a natural way of being. So we have to very diligently get this stuff out of our diet. And then over time,
00:35:54
chrisyzen
to get out of our body but that that process takes time which is why you have to just completely if you're if you're truly truly serious about maintaining your health or restoring your health or you know having um longevity um increasing your longevity then this has to be like one of the top few things certainly top 10 certainly probably top three possibly top the number one thing and for the most part it's it's quite easy you just change things you're doing on a daily basis you almost all people have to grocery shop or order food online right so you just make some changes to what you buy what you put in your body what you consider food if you make that change and then stick with it you are going to
00:36:52
chrisyzen
do all those things, increase your longevity, restore your health if you need to restore your health and maintain your great health. Simple as simple as but the the the problem is that the simple things aren't necessarily easy. And I know it's not easy. um But look, if I can do it after the way I lived for 30 years, well, let's say in my late teens and 20s, if I if I can turn all of that around, I'm sure you can, you know, so Anyway, thanks for listening and watching and I'll see you on the next episode.