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Mechanisms of Autoimmunity: More Reasons Gut Health and Toxin Reduction are Crucial

Connecting Minds
Connecting Minds

305 plays · Mar 26, 2023

Health consulting - adults: https://christianyordanov.com/health-consulting/  Children's health consulting (autism, ADHD, gut dysfunction, etc.): https://christianyordanov.com/childrens-health-consulting/ Some common health complaints we can help you address: * Fatigue / low energy / running on coffee * Low libido / hormone imbalances * Gut problems * Sleep issues * Brain fog * Anxiety / feeling too stressed * Headaches * Blood-sugar dysregulation * Excess weight Links to my book Autism Wellbeing Plan: How to Get Your Child Healthy: US Amazon: https://www.amazon.com/Autism-Wellbeing-Plan-Child-Healthy/dp/1916393004 UK Amazon: https://www.amazon.co.uk/Autism-Wellbeing-Plan-Child-Healthy-ebook/dp/B084GBBDL9 My podcast, Autism and Children's Health: https://podcasts.apple.com/us/podcast/autism-and-childrens-health-lab-testing-diet/id1512380225 Get 3 FREE video courses instantly when you sign up to my members' community here: https://members.christianyordanov.com/ The courses are: * The Healthy Gluten-Free, Casein-Free Diet for Autism. ADHD, and Gut Dysfunction * Nutrient Supplements for Autism, ADHD, and Children's Health * Health Challenges Autistic Children Experience You will learn a ton and there will be more educational content for parents on the free member plan. Members can also suggest topics for me to research and publish in the community platform. Join us today: https://members.christianyordanov.com/ The above 3 courses cover topics such as gut dysfunction and infections, clostridia bacteria, Candida, oxalates, methylation, excitotoxicity, zinc / copper imbalance, going gluten-free and how to do it well, heavy metals and chemical toxicity, probiotic supplementation, mitochondrial dysfunction, immune system dysregulation, neuroinflammation, and much much more. I even show you how to select high-quality supplements and avoid the junk and hype - with real examples and analysis of ingredients on screen... Every parent of an autistic child must know this information that is why I want to share it with you for free. And parents with kids that have an any health complaint will also learn a ton. In fact, every parent will learn a lot of value information from each of these courses - so please help me share this information with more parents! Thank you so much. Website: https://christianyordanov.com/

Transcript

Speaker: Hi, Christian Jordonov here. Thanks for stopping by. Today I want to have a brief discussion on some of the mechanisms through which autoimmunity can develop in the body. And this will underscore why

Speaker: Gut health and gut lining integrity is so crucial and also why toxic exposure reduction through diet, air, water and products that you use is also super crucial

Speaker: in order to preserve health or get back to a state of good health. Whether that's for your children or for yourself, these terms or these concepts will cover

Speaker: really apply to children and of course anybody, right? So I'll be just going over some stuff from a chapter in my book, Autism Wellbeing Plan, How to Get Your Child Healthy.

Speaker: Check out the book if you haven't if you are interested in the auto autism aspect and children's health aspect but for adults again the mechanisms are basically the exact same except when you have an adult.

Speaker: You've already gone past the neurodevelopmental stage, so autoimmune reactions are going to have different manifestations in the body. So it affects children, it affects adults. So a couple of things we want to get out of the way, just to give you a primer on

Speaker: the terms that relate to the discussion relating to the immune system that will cover. So obviously, you know what the immune system is? It protects you from pathogens, foreign invaders. It monitors the blood for anything that it doesn't recognize. And if it doesn't recognize something, it will create

Speaker: that's an antigen, some type of could be a piece of undigested food, it could be a chemical, heavy metal, an infectious organism. So that is the antigen that the immune system will quote -unquote label or tag as a foreign invader, something that must be neutralized, excreted and so on.

Speaker: When it recognizes something as an antigen, the immune system will create the antibody. Now the antibodies, they're also known as immunoglobulins. So if you see like a food sensitivity or allergy test, they talk about IgG antibodies or IgE antibodies, right?

Speaker: So you've got your antigen, your antibody, right? Now the antibodies are created by the, there's what we can call the adaptive arm of the immune system. It's also called the humoral immune response. And you also have the cell mediated or innate immune system, right? So there's different mechanisms, but when it comes to

Speaker: antibody creation, antigens and stuff like that. We use the adaptive arm. So this is like the immune system that gets trained.

Speaker: from basically day one of life. As we're exposed to various different chemicals, particles, bacteria, et cetera, the immune system starts making antibodies. So let's say the first time you have a lot of these childhood illnesses, whatever, measles or other stuff, you have it once generally.

Speaker: You your body fights it for for a few days or whatever you mount that antibody response and now you've got your Antibodies for life usually and then you should not you should not probably in the future You know get sick from that thing because you have the antibodies you have your little soldiers that are ready to attack it right and neutralize that particular Whether it's a whatever illness it is right now

Speaker: Now, here's where things can go wrong. So we have antigens and antibodies.

Speaker: When things get dysregulated in the immune system, that's where autoantibodies start getting created. So this is one of the main mechanisms of autoimmune disorders. And basically what an autoantibody is, it's an antibody

Speaker: created that targets part of your cell or your child's cell a protein or other tissues of the body that could be a brain cell like a neuron or something in the nervous system it could be the gut like in celiac disease any number of tissues can be attacked it could be the cartilage and the joints and

Speaker: This is where we can classify or the medical system classifies different types of autoimmune diseases and disorders depending on what gets attacked, right? So the question then is, why does the immune system start doing this? Why does it become dysregulated? And this is a quote from my book. The question remains,

Speaker: This is from a paper that I cite in my book. Quote, the question remains, what is causing the chronic immune activation of the brain? This is related to autism.

Speaker: We believe that there is compelling evidence that excessive systemic immune stimulation through a combination of numerous and closely spaced vaccinations, immune and excitotoxic effects of mercury additive thimerosal, systemic infections, food allergies, candida infections and genetic factors all play a part."

Speaker: So a number of internal or external stressors can perturb the immune system, both again of a growing child or an adult, right? So infections, allergies, toxins in food and medications and so on, right? So it comes down to genetic variation, what you or your child is susceptible to, right? Someone might be more

Speaker: It could be more of a brain thing. It could be more of a joints thing. It all depends on the predispositions we have. And then, of course, the toxic onslaught that dysregulates the immune system. So it all starts really with some type of immune system dysfunction. And the

Speaker: When it comes to children, the maternal environment, so the health of the mother, whether she has autoimmune conditions to begin with like diabetes type 1 and so on, these play a part, right? But then as you are born and grow, other things can disturb your immune system like allergies,

Speaker: activation of certain immune cells, again caused by various toxic compounds, chemicals, heavy metals, excessive inflammation, which again can be caused by these external compounds or bacterial infections, candida, stuff like that, and leaky gut or intestinal permeability. This is another thing which

Speaker: can go hand in hand with, again, gut infections, candida, heavy metals, and toxic chemicals. And then inflammation is invariably going to be involved here, right? So the two main, so you have a little bit of a primer, how this kind of stuff can develop. Now, what I wanted to

Speaker: Cover is a couple of the mechanisms because this will underscore the importance of cleaning up your child or your own diet. When I say cleaning up the diet, I mean

Speaker: switching over to organically grown produced food that does not use all these chemical pesticides, poisons, artificial fertilizers that can have some deleterious chemicals in them and herbicides, glyphosate, and of course removing processed foods that are full of emulsifiers and other horrible chemicals as well.

Speaker: So that's one thing. And then the other is cleaning up the environment again from toxic exposure. So switching from aluminum, cookware to stainless steel, cast iron, just buying more natural cleaning products, just so many things. And I have podcast episodes that cover these things in more detail. So the two mechanisms that we'll cover now to get to the meat of this topic,

Speaker: They are cross -reactivity, also known as molecular mimicry, and the formation of neoantigens, so new antigens. So cover cross -reactivity or molecular mimicry first. So this is another quote from a paper I cite in my book on autism.

Speaker: quote, due to the similarity of food proteins and infectious agents to human tissues, antibodies produced against the food and infectious antigens may also attack human tissues. So again, this can be triggered by food proteins

Speaker: and infectious antigens, so infections. So this is where we're not talking about gut health and why it's so important, right? Why you have to understand if you or your child have a gut infection, candida overgrowth, very, very common with autistic children, actually. You should know that by now if you listen to my Autism and Children's Health podcast. So now these tissues that can get attacked

Speaker: can be a part of a brain, the gut barrier or anything else in the body as I've already covered, right? So you've got your antibody that is roaming around in the blood, looking for the antigen to attack the bad guy. And before it sees the actual bacterial toxin, let's say, it sees your tissue, your body's tissue, let's say a cell in your nervous system, and

Speaker: It attacks that because it mistakes it for the antigen of the infectious particle or bacteria or whatever it is. Now what can happen here is it attacks the body and this can lead to a vicious cycle.

Speaker: It thinks there's more of these guys and more antibodies get created. So now all the similar looking tissues in the body, there's a higher chance there's more antibodies for them. There's a higher chance they can get attacked and damaged and that causes inflammation, right? Causes further tissue damage. Now other bits can break off from that tissue that

Speaker: because they're not the the full protein they're different now the the immune system may again mistake them for a foreign invader and we'll cover that a little bit later right so basically what you must understand is what

Speaker: What are cross -reacting antigens? And some of the most common ones in food are things like soy, wheat, or cow's milk proteins, and certain heavy metals like mercury, various chemicals that I don't really have the time to get into, and infectious agents again, so bacterial toxins, candida, and viruses allegedly, right?

Speaker: So these are potentially cross reacting foods. Okay. Now the other mechanism that we'll cover briefly is the formation of neo antigens. So these, um,

Speaker: These basically, Neo as in new, right? Basically what happens is when you have like a heavy metal particle or a chemical or whatever other particle, even certain food particles, right? They can actually

Speaker: bind with our own tissues. They kind of like hit them and they get stuck in them. If you can imagine like throwing a brick into a window, that kind of way. Not the best example, but it gets stuck in the tissue, like it crashes into it. So through that, it creates a new structure.

Speaker: or a complex. That's what the researchers call a neoantigen. Now, this neoantigen, because it has a different structure, the immune system doesn't recognize this particular, you know,

Speaker: structure. So this can cause the immune system to react very strongly, right? Now here's another quote from a paper I cite in my book.

Speaker: The act of binding to tissue also breaks down tissue, causing tissue antigens to free flow through the bloodstream. Here the immune system will identify these tissue antigens as unwanted materials and thus make antibodies against them. Once the formation of all two antibodies occurs, tissue degeneration may follow.

Speaker: This is autoimmune reactivity. If the exposure to the environmental trigger is not eliminated, the tissue destruction will continue to the point of autoimmune disease.

Speaker: Okay, so you have your body's tissue, something gets stuck in it. Now you got your antibodies, your immune system creates antibodies because it didn't recognize that as part of the self. You got your antibodies attacking that, that causes damage, inflammation and

Speaker: pieces of tissue, whether that's cells in the, you know, could be the pancreas, it could be any organ really in the body, could be blood vessels, whatever, pieces of that break off. And let's say if it's one, like in the case of a house, if it's a brick,

Speaker: It's very easy to understand that's part of the house. But if it's like several bricks stuck together with cemented mortar, that's a bigger piece. And now the immune system is only used to like seeing either mortar or bricks. It's not used to seeing like six bricks in that particular shape. So it's like, okay, that's something you have to attack. And now the antibodies that get created

Speaker: they, if they spot that pattern of six bricks in the body, let's say, they, that also will start getting attacked. So this is where you can get the, so the, the, um, the more of these triggers there are, the more damage occurs.

Speaker: And then the more degeneration occurs and then that feeds the vicious cycle because now you have more different tissues breaking down, new antigens, more antibodies, more autoimmunity, more damage, more inflammation, you know, further sort of compromise of the gut.

Speaker: further compromise of the blood -brain barrier. And then, you know, once the blood -brain barrier sort of gets breached, you know, we've got a recipe for really, really horrendous disease to occur.

Speaker: So you can see now why the old adage death begins in the colon or old disease begins in the gut, you can see why

Speaker: we talk about the importance of the gut. It's linked to pretty much all conditions, or at least it's got a, it's a big, it plays a large factor. And with my work, at least just to give you an example with autistic children, and what I advise parents in my book is if you were to force me to tell you what area is the most important to focus on,

Speaker: it's the first thing I would say is get your child's gut health in order. And if you came to me with as an adult, let's say, and you had like skin problems, or anxiety, or you know what, most things I'll tell you is the first thing we will do is run some tests that look at gut function, whether

Speaker: there is candida overgrowth, whether there's parasites or opportunistic bacteria or pathogenic bacteria that have invaded the gut, you know, or we can look at some, you know, the numbers of the beneficial microbes, are they reduced, so on and so forth, right? And I should mention that if you do need help,

Speaker: If you do have some issues that you want some advice on, get in touch. There's links down below for health consulting for children and for adults, separate pages, check that out. You know, we've had some amazing success with getting people back on track with like

Speaker: a decade or more of irritable bowel syndrome, things like that, autistic kids with pretty nasty bacteria and candida overgrowth and so on and so forth. Even in a few months, you can really have some amazing results. So if you are interested, get in touch with me. Links are below in the description.

Speaker: Yeah, this is why the gut, you have to really protect yours and your family's guts like you would, I don't know, like you would protect the treasure because this is where it's at. And again, this is super important to remember, if you have gut issues, they will not just be physical

Speaker: health problems that you will see. You could have only quote -unquote psychological problems, quote -unquote behavioral issues in children that could be the root of that or one of the cause of factors or contributing factors

Speaker: is very likely to be the gut. So this is what people must understand. It's not necessarily going to be just like you have gut problems, you're going to feel pain in your gut. This is what you have to understand. You have gut problems, you will not necessarily have constipation, diarrhea, gas, bloating, stuff like that. Often you will, but sometimes it could just be a headache. Seriously, you just get a headache.

Speaker: It could be something related to intestinal permeability or leaky gut, food sensitivities and so on. It's what you must understand of sleep problems or moodiness because the bacteria in your gut, they create

Speaker: neuropeptides, neurochemicals, neurotransmitters, serotonin, they can interfere with conversion, like if you have toxic bacteria and their compounds or metabolites,

Speaker: They can interfere with the conversion of certain neurotransmitters, right? Those metabolites. So that can cause strong behavioral effects in the case of autism. In fact, the Clostridium bacteria, anyone can get it, Clostridium difficile.

Speaker: It exudes a particle or it excretes a particle called for creosol and that de -inactivates an enzyme in the nervous system called DBH, dopamine beta hydroxylase. And then, so I believe it's in my book, just off the top of my head, that enzyme,

Speaker: converts dopamine to norepinephrine. And if you have a lot of Clostridia, which a lot of Clostridium difficile, a lot of autistic children do have, I'll tell you. And we can test that on the organic acids test with the Great Plains Lab. So that

Speaker: for creosal metabolite, it inactivates this DBH enzyme. So that causes a buildup of dopamine in the nervous system. And dopamine is extremely reactive. It can cause damage and oxidative stress that can damage nervous system tissue. And can you see now how

Speaker: That can have, like if you damage nervous system tissue, can you see how that will have, you know, neurodevelopmental manifestations in children or potentially neurodegenerative manifestations in older folks, right? So, okay.

Speaker: Just to summarize what particles, to get back to this formation of neoantigen section, what particles we know that can bind with human tissue and create these new neoantigens. These include mercury, aluminum or aluminum, BPA or bisphenol A, formaldehyde,

Speaker: and artificial food colorants are known to do this. Certain dietary lectins and glutenins. So, for example,

Speaker: Gluten is an example of a lectin, which is basically a protein in plants or in organisms. And gluten can actually bind with tissue. So this is why gluten, going gluten free case in free, especially like, for example, for ADHD, autism, anytime there's gut dysfunction in adults, children as well.

Speaker: going gluten -free and even case dairy -free is very often a good idea, at least for a while. Let the gut heal, let the immune system calm down a bit. Now, let me get into, so I just sort of emphasized why the gut

Speaker: is so important to be kept in a healthy state. And we wanna ensure as few toxic particles are allowed to enter your body or your child's body to keep the gut in good check, right? And why we want to test for infectious organisms and do something about them. Or if you can't afford the testing

Speaker: at least invest in like a pathogen eradication protocol, like a cleanse and do that once, twice a year. So I've, excuse me, I've done tests on myself and of course on my family members, friends, obviously clients, but for myself, what I do now is twice a year when the seasons change,

Speaker: uh, spring when spring sort of, when we entered into springtime. So about now in March and, um, September when, you know, we go, we get into autumn. What I do is a, um, basically I do a parasite cleanse. I use various antiparasitic herbs, uh, diatomaceous earth.

Speaker: olive leaf extract, they've got some really good supplements that are readily available and easy to find, fairly inexpensive. So I do that along with the Goldbladder Flush, I've discussed that in the future. There will be a video course on that coming out soon. So I do that a couple of times a year and this protocol, we can do it for a week, 14 days, it depends on if you feel like

Speaker: If you feel like you may have parasites if you're waking up a lot like a three three or so a .m. At night you can't fall back asleep if you have like itchy itchy butt Or so, you know, if you feel like you have got dysfunction you

Speaker: You know, obviously I would recommend working with a practitioner. You don't want to just guess and do kind of, you can, it's very easy to do something, you know, that can cause harm as well. So you need to, you need guidance. I believe, but, um, so what, what I do is a couple of times a year I do this, whether or not I believe I have a,

Speaker: An overgrowth or not because I have had I have had Excuse me. I have had parasites and very high candida And certain dysbiotic bacteria. I've had that a few years ago. So It's it's basically like a Reset I do so even if something when I did that big massive protocol back in 2019 to

Speaker: kill them off, you know, to normalize all that stuff. Even if something survived, or I caught something in the past years being outside, and you will always, you know, have exposures, I just do this like a mini reset every six months or so. And, you know, that, that keeps my gut healthy. You know, if, you know, if, if there is nothing

Speaker: If there's nothing quote -unquote bad in there, taking these herbs, it doesn't have side effects like taking antibiotics or toxic drugs. Curbs may have side benefits in fact, right? So they have anti -inflammatory antioxidant properties and through hormesis they can stimulate antioxidant production in the body and so forth, right?

Speaker: That's the gut stuff. You can see I can talk about this ad nauseam, as you can probably see. I can absolutely chew your ear off on the many different reasons we have to keep our guts healthy. But I almost sort of lost my train of thought there what I was going to talk about. It was the

Speaker: It was the other component.

Speaker: of reducing toxic exposures that I wanted to touch on as we slowly wrap up this episode. So you now understand the importance of the gut because you want this gut barrier to have integrity, to not have permeability. You want that to, because here's the next sort of, let me segue into the toxic substances.

Speaker: If you've got microbiota in good check and you have no bad overgrowth of candida and pathogenic organisms and you have minimal permeability between your gut cells, toxic metals and chemicals now are harder to get into your bloodstream because

Speaker: You have your microbiota, you have your gut cells, there is layers of protection. This is the importance of keeping inflammation low. Now, however,

Speaker: On the other side of things, if you, let's say, you know, drink water with arsenic and other heavy metals and toxins that you're not filtering out, and check out my previous episode on talking about water distillation, reverse osmosis and the importance of water, obviously clean, pure water.

Speaker: But if you have an onslaught of toxins from the diet in the water into your body because you're not investing in organically grown food or some folks just don't have it available to them.

Speaker: you know or you eat a lot of processed foods or your child eats a lot of processed foods which have chemicals like there's more than 2500 chemicals in foods that are used regularly from emulsifiers to you know preservative stabilizers food colors

Speaker: flavors, excitotoxic things like monosodium glutamate and many others, right? So even if you have a pristine gut now and there's no leakiness or no permeability and it's in good shape, if you start eating foods that are contaminated with heavy metals and these chemicals, now you can actually start, you can lay the foundations for autoimmunity

Speaker: through basically the following. You've got these heavy metals, chemicals. These can damage the gut, right? They can get stuck into tissues. They can cause tissue damage. That causes inflammation. That causes immune system activation. That can cause, again, talking about the vicious cycle, further inflammation,

Speaker: Now you have new neoantigens, now you're creating more antibodies, now there's more tissue damage, now the gut becomes leaky. And now, if you continue these environmental, these triggers that you're taking, heavy metals, chemicals, whatever it is in the diet, in the water, if that continues, now you've breached the gut barrier. This is where things can get potentially nasty for a person.

Speaker: You've got the blood barrier, sorry, you've got the gut barrier breached. Now these things are getting into your bloodstream. And this goes back to the stuff I already covered. So they're tagged as antigens, antibodies,

Speaker: and then further immune system activation, further inflammation, further tissue damage. And again, so this is another way to enter this vicious cycle. So even with a perfectly healthy gut, if you don't do something about toxic exposures, you are now potentially getting into this vicious cycle. Okay. So this is why a pristine diet, especially when someone has a condition like autism or

Speaker: Alzheimer's or you know, IBS or Frank autoimmune conditions. This is why diet and environmental exposure are the most important things in any, any, think about any situation you can tell me.

Speaker: I don't care what level of health we're talking. Are we talking perfect health of an athlete or extreme, you know, even cancer and just extreme disease? The first things you want to get right are

Speaker: decreasing toxic exposures, reducing these environmental triggers, and improving gut health and the diet. So I guess it's three things though, but you understand what I'm talking about. So this is the other kind of vector that can lead to autoimmunity over time. And that's not all, unfortunately.

Speaker: Here's the thing, the gut barrier, the tissue of that, so the cells and the tissues that create the gut barrier, they actually use some of the same proteins as are used in the blood brain barrier, right? And the blood brain barrier is again tissue in regions of the brain that protects parts of the brain from

Speaker: toxic onslaught basically, right? So if you have antigens or neo antigens that are tagged by antibodies by the immune system that are to the, let's say, okay, here's the example. You got, you know, some tissue damage inflammation in the gut pieces of the

Speaker: the gut barrier get broken off and these are tagged. The antibody as it circulates around your circulatory system, your blood circulation system. If it is in the vicinity of the blood brain barrier, it can actually now mistake

Speaker: tissue of the blood brain barrier as that antigen that it was made to find an attack, you know? So now you've got your blood brain barrier can start getting attacked, right? And once the blood brain barrier is open,

Speaker: And not necessarily just the blood -brain barrier, right? Any time the immune system targets neurological tissue, so that could be nervous system tissue in your central nervous system, for example, and stuff like that, or peripheral nervous system, when if this goes long enough and you start creating antibodies for neurological tissues, now,

Speaker: that damage as it builds, as it builds, you know, if it happens for a while, let's say you catch it six months in or whatever, and you heal the gut, you know, reduce toxic exposure, so on, do all this good stuff, maybe you don't feel anything. But if it goes unrecognized for months and months and years,

Speaker: Now this damage to the nervous system or these neurological tissues can manifest as behavioral issues, movement disorders, communication difficulties. So again, to delineate between children and adults

Speaker: With children, we have neurodevelopmental type issues, conditions, because the brain nervous system and all these sort of systems communicating and working in sync, they're not fully developed. So that manifests as autism and things like that, right?

Speaker: In some people, like I'm not saying every autistic person or every autistic child has neuro -ultimunity or neuro -inflammation and so on, but it is, there is a component, there is a subset of children that do have this, this, this is what I'm talking about.

Speaker: is from my research on autism. But again, it applies to folks of all ages and stages, because in terms of older folks, we have

Speaker: various conditions related to neurodegeneration. We have Alzheimer's, it's the easiest thing to list. I honestly don't care much for learning too much about the thousands of different conditions and so on because

Speaker: Let's say, quote -unquote, the best way or the way to get a person healthy. The principles are pretty much the same, no matter what they have, with obviously some caveat to some complexity there. But on a high level,

Speaker: It's really about diet, lifestyle, environment, water, you know, toxin reduction. So the point is, in older folks, this can be like ataxia, you know, like when loss of coordination in movement, loss of speech, you know, things like that, just kind of dementia, right? So this is what you must understand. And again,

Speaker: I don't want my podcast and my content to be doom and gloom.

Speaker: I do want to offer, as much as I educate folks about staff issues, I want to offer solutions and a way forward. And this is really, I suppose, this is what we have to extract from today's discussion of this issue. Let me just before I continue that thread, just want to end the

Speaker: the, give you one last citation from a study. Um, actually two, I'll give you two. So in terms of this is again, from my book on autism, quote, from, from a research paper. Quote, the earlier the environmental triggers are detected and removed, the better will be the clinical conditions of ASD patients. Right. So the earlier the environmental triggers are detected and removed.

Speaker: And then another quote from a research paper called, while a panacea for such a heterogeneous disorder may never exist, evidence suggests that manipulation of the immune response could improve core features of ASD as well as associated aberrant behaviors. Okay, the language is not very PC in a lot of these researchers' papers, but point is,

Speaker: Immune system dysregulation, that's why it's chapter two of my book. Immune system dysregulation is a huge part of autism and many, many conditions, you know, allergies and, uh, God, you can just, uh, basically any auto immune type thing, you know, there's,

Speaker: The music and here's the thing i know i keep going back to the gut but you got sixty to seventy percent of your immune cells are in and around co located in the gut.

Speaker: which came first, the chicken or the egg, which came in terms of health issues, which came first, the immune dysregulation or the gut dysfunction. Because immune dysregulation can cause gut dysfunction. Gut dysfunction will cause immune dysregulation if left unchecked.

Speaker: How do you know if your or your child's immune system is dysregulated? So I'll tell you some of the most common physical clues. So food allergies, food sensitivities. And again, let me stress this. You will not necessarily know. You have a food sensitivity just by even monitoring your reaction after food. It won't necessarily

Speaker: appear as symptoms like physical symptoms, you know, or if it's if you're in the early stages, you might have no symptoms. It might take months, sometimes years for you to actually get symptoms. And again, they don't have to be gut symptoms. Many, many new, you know, sleep, skin problems, headaches, mood stuff, neurological stuff.

Speaker: It can manifest as only that and you may even notice nothing related to your gut and many people are like that and sometimes it takes me getting them a food sensitivities test

Speaker: And then they see like they have like three or four or five foods are like off the charts in terms of antibodies, not because you have like the delineation on these tests, you have like, you know, safe or minor, you know, you have yellow, you know, green is low, you know, yellow, orange, red and then red. And then some people are off the charts, seriously, like for, you know, gluten, for example, or

Speaker: One that is very common I've seen it in adults and children is meat glue. If you processed meat, meat glue is actually something we can test for and a lot of people react very reactive to it. So again, goes back.

Speaker: well and I do I do actually I do have an episode on gut how to fix your gut it's called I believe on my connecting minds podcast and the reason I'm saying what podcast it is on is because I will publish this episode probably to two podcasts of mine the autism and children's health and connecting minds and I'm also

Speaker: planning on starting a third podcast, just Children's Health, the Children's Health podcast. So in the future, you can check that out. That will be just more general Children's Health. But yeah, so

Speaker: So just to kind of go back to, I keep going on some tangents, I'm sorry if it's hard to follow. So common physical clues that your child or your own immune system is dysregulated include, again, food allergies or sensitivities, obvious adverse reactions to foods, chemicals or medications.

Speaker: chronic gastrointestinal symptoms. This is the most obvious thing. Constipation, diarrhea, excessive gas, bloating. But let me just emphasize. So these chronic gastrointestinal symptoms of constipation, diarrhea, excessive gas, or bloating are indicative of gut issues, obviously.

Speaker: But the points I'm covering here are these are clues that your child or your own immune system is dysregulated. So if you have gut problems and you've had them for a number of months or more,

Speaker: then it is even more likely that you have some type of immune system dysregulation. And left unchecked, over time, that things can happen, especially if you just continue on a path of poor diet, a lot of stress, working too hard. There's so many things, maybe you're going to the gym, over training, these things will over time build up.

Speaker: And another common clue is when children especially, so a lot of recurrent infections, like ear infections, chronic sinusitis, or if you get sick a lot, like if you get a cold or the flu like three, four times a year, listen, don't let anybody tell you that's normal, or that you have kids and kids are bringing you viruses,

Speaker: from school and listen listen that those are I'm sorry excuse my language those are bullshit excuses the reason people get sick a lot with you know minor cold and stuff like that is not it's not because your kids okay it's because

Speaker: I'm going to go out on a limb and of course we can do lab tests and stuff like that and analyze diet and lifestyle. But I'll tell you in most cases, it's because your health is not as optimal as it could be. It's diminished.

Speaker: You probably have some type of gut dysfunction you're not aware of. You are probably pushing yourself too hard. You're not eating well or well enough. You're probably getting a lot of toxic exposure from food, from traffic and stuff like that. It could be other factors as well, of course.

Speaker: But let's stop making excuses that we get sick a lot because our children are bringing us viruses back from school and stuff like that. Let's get our health in order.

Speaker: And you see that for me, not that I'm surprised or disappointed. We've had a very tough couple of years with my wife because we had a child and that was obviously sleep.

Speaker: sleep sort of goes downhill and diet definitely wasn't as good as before when we had time at least for a while now it's much much better of course it just we had that we had like a the first sort of year was was a little bit survival mode basically survival mode so we're starting to crawl out of that place but you know and I understand why people were in

Speaker: in the stage there i'm not judging or anything but i'm just saying we let's not make excuses let's take responsibility and if we want to and fix things we can. Okay so.

Speaker: Final point, and there will be more content related to this and other similar topics in the future. Don't worry about it. If this was interesting to you, there will be much more interesting things coming up. But let's just briefly talk some of the things that in the future will cover a little bit more. So what are the

Speaker: So in terms of children, basically, if the points I covered above

Speaker: are present in a person, child or adult, that are clues that there is some type of immune system dysregulation. So again, food allergies, sensitivities, adverse reactions to foods, chemicals, medications, chronic gastrointestinal symptoms, recurrent infections. If these are present and it does signify immune system dysregulation,

Speaker: Some things that can be done, ideally with the help of a practitioner, of course, that knows what they're doing is, for example, like you can go to your doctor, especially for children, if you haven't done an allergy test, identify any allergies and eliminate allergens from the diet and environment, right?

Speaker: in terms of adult and children's health, identify food sensitivities. This is something that really is super, super prevalent, right? Super prevalent and, you know, for

Speaker: $150, $200, you can do a food sensitivities panel that can test for like a couple hundred foods. I do one, I send one to my clients where you receive the, it's like a little, basically it's a card, like a paper card, you just poke

Speaker: Prick your finger and you just put a few spots of blood on it. Yeah, let that dry for a day. You package that or you put that in an envelope, send it back to the lab and it's a really good test.

Speaker: and you will quickly know what foods to remove from your diet or from your child's diet because these foods are causing inflammation, immune reaction, and they're contributing to the vicious cycle. What you want to do is identify as many of the factors as you can and stop those things from progressing to stop the vicious cycle. The other thing you can do

Speaker: is remove other potentially cross -reactive or inflammatory foods and additives. So again, processed foods, that's junk. Stop buying that junk, okay? Potentially cross -reactive foods, if you eat soy, let's say you did a food sensitivity test, but for example, wheat or dairy or soy, or all three didn't come back as reactive, but other things did. You may want to

Speaker: while your gut is sort of getting in better shape, you may want to go gluten free, or casing free, or both, or remove soy, or corn, or all grains. A lot of people, listen, grains can be very inflammatory, especially how we are over consuming them and not preparing them in the ancestral way. So you may want to,

Speaker: do let's say you do have got dysfunction and you know we find out on the test you may want to just remove grains for six months or maybe more depending on how bad how bad things are of course. Now goes hand in hand with the next point you want to identify and address gut infections that are causing immune activation and again you won't necessarily have

Speaker: super visible symptoms like with candida with you know a lot of people I actually I would say

Speaker: The majority of people that we have through lab testing in my practice that we have found some type of dysbiotic marker on a test like candida, clostridia difficile, stuff like that.

Speaker: they didn't actually have overt gut dysfunction like you know your common symptoms like constipation, diarrhea, pain when eating, bloating, gaseousness and stuff like that so it very often is hidden this stuff is hidden yeah and then this next point goes hand in hand with the previous one you want to support gut healing with a healthy organic diet

Speaker: and supplements, supplements really help speed up the process. There's just certain things you won't be able to get enough of from your food, right? And supplements is something I've done a ton of research into and I'll cover in a lot more detail in the future. So not going to get into it now. And then in some cases when we're talking about specifically suspected alter immunity or like a family history,

Speaker: about immunity. There is some tests that for clients in the USA and Canada, maybe Mexico, I can't remember if Mexico also is included, but USA and basically North America, Canada and USA, we can run

Speaker: pretty specialized, quite advanced tests that test for autoimmune antibodies. So antibodies that target specific tissues, like neurological gut tissues. So it's a pretty advanced test, not the cheapest thing either. But in some cases, you know what, it's worth running because in some cases, these things can

Speaker: Once you reach a certain threshold, they can progress or cause degeneration super quickly. As we've already covered today, you want to

Speaker: Identify, reduce environmental triggers and get the gut healthy as quickly as possible and keep it that way. Don't just regress to after a year or whatever, you feel better and then you start, oh, have a pizza here, oh, I'm going to have an ice cream there. And then slowly that vicious cycle begins expanding and becoming more serious again.

Speaker: So that, I will leave it there. I think I covered enough stuff and it's been an hour. If you are still listening, thank you so much for tuning in. Check out the links below. I have three video courses. This is more for children's health related with a focus on autism, but any parent would find value in these courses. You will learn not just

Speaker: valuable stuff for your children, but for your just health in general. It's on the gluten -free case, in -free diet, nutrient supplementation and the health challenges in autism. So these three courses are available for free. It takes less than a minute to sign up to my member platform on the free tier. You get instant access to those. There's at least six or seven or more hours of content there, I believe.

Speaker: And you can have that. And there's probably by the time you hear this in the future, if this is the future, not not the next few days after I publish this, there will be more content there, free content for you to, you know, look, you know, look over read. And then my website should have a have a start organizing things into specific health topics that you may want to check out again, not

Speaker: Not if you're hearing this now, today, or tomorrow when I publish it, but soon. So I will, of course, let you know again in the future. Again, thank you for tuning in to the podcast. Christian Jardinoff signing off. See you on the next one.

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