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Lipid Peroxidation's Role In Aging and Disease  image

Lipid Peroxidation's Role In Aging and Disease

The Live Longer Formula | How to Actually Live Longer
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Are you following health trends that actually harm your body? In my eye-opening masterclass "The 7 Popular But Deadly Health Fads," I reveal how common health practices promoted by influencers and gurus might be ravaging your gut, accelerating disease, and shaving years off your life.

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The Live Longer Formula is your go-to podcast for cutting through the noise and discovering practical, science-backed strategies to not just add years to your life, but to add life to your years. Hosted by longevity author and functional health practitioner Christian Yordanov, this podcast dives deep into the truths (and myths) behind longevity, health optimization, and addressing chronic health problems.

Each episode offers actionable insights drawn from the host's own research, clinical practice, and personal journey, helping you make informed decisions to restore and enhance your health. Whether you're interested in reducing stress, boosting your energy and mental performance, improving your gut health, or simply looking to optimize your diet and lifestyle, this podcast delivers the tools you need to live a healthier, longer life.

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Transcript

Introduction to Christian Jourdanoff

00:00:01
chrisyzen
Hi, thanks for tuning in again to the show. Christian Jourdanoff here, functional health practitioner and author of the book, How to Actually Live Longer, volume one.

Topic Introduction: Lipid Peroxidation

00:00:13
chrisyzen
Today, I want to talk to you about a very important topic, lipid peroxidation. We'll define that in a minute if you're not exactly sure what that means.

Is Aging a Disease?

00:00:22
chrisyzen
And aging, and we could absolutely lump in disease development slash prevention in in in sort of this area of discussion that we're we're going to tackle today.
00:00:38
chrisyzen
The reason longevity or aging and disease development, progression or prevention can be tackled at the same time is because a lot of researchers are already basically equating aging to to being a disease, really. Because while I personally don't think necessarily it's a disease, a lot of
00:01:07
chrisyzen
a lot of the same mechanisms that underlie disease development progression, underlie aging.

Addressing Factors of Aging and Disease

00:01:15
chrisyzen
So if we can figure out what those are and then with a little bit of evaluation of a human and a little bit of lab testing and some clinical assessment, we can figure out what are the factors in their diet lifestyle, stressors, nutrition, deficiencies, all that stuff, toxins, gut health, what are the Factors that are accelerating their aging and by virtue of that, the the progression of disease, which means they will likely develop some type of something diagnosable earlier in life than otherwise. If we if we address those things after we identify them, we address them.
00:01:53
chrisyzen
with diet supplementation, stress reduction, you know, all that good stuff, gut health detox stuff. And that will allow them to age more slowly. And again, that means they are less prone to those kind of disease processes, overwhelming them to the point where they can go to the doctor with some complaint and the doctor will say, well, you got XYZ disease, according to whatever criteria, right?

Omega-3 vs. Omega-6: Susceptibility to Peroxidation

00:02:22
chrisyzen
So, lipid peroxidation. If you if you're listen to the episode I did on omega-3s a couple of weeks ago, this is a little bit of a continuation of that theme, because as you soon see, lipid peroxidation, really it's the polyunsaturated fats in our tissues that are the biggest culprit here. That doesn't only include the stuff from the seed oils, the omega-6s, but also omega-3s.
00:02:49
chrisyzen
which as you will as you will soon see are even more fragile slash more peroxidizable than the Omega-6s. Let's start at the beginning here.

Diseases Linked to Lipid Peroxidation

00:03:01
chrisyzen
I asked Chad GPT three questions today that were so sort of simple that the little bastard could not screw me over with a roundabout bollocks answer, basically. So the first question I asked it, what diseases slash conditions is lipid peroxidation associated with? And it responded, lipid peroxidation is a process in which free radicals, particularly reactive oxygen species or ah ROS, oxidize lipids in cell membranes leading to cell damage.
00:03:42
chrisyzen
This process is implicated in the pathogenesis of several diseases and conditions, primarily due to its ability to induce oxidative stress and promote inflammation. And if you have been listening to me for any length of time or you have bought my book how to actually live longer volume one,
00:04:01
chrisyzen
you know that I in my little sort of the three primary drivers of aging and dysfunction in that little of hierarchy I have stress at the top and then oxidative stress and inflammation would be the other two those are the three primary drivers of aging and dysfunction and they they enhance each other's effects so they kind of there's a lot of overlap and you know obviously that means that oxidative stress will promote inflammation, likewise inflammation can promote oxidative stress and it is a stressor in the body, it will raise cortisol because it's an anti-inflammatory anti-inflammatory hormone as well as a hormone that raises our blood sugar.
00:04:44
chrisyzen
So that's what lipid peroxidation is. It's basically our cells and or their components constituents getting damaged and it's the fatty acids in them that get peroxidized that causes this lipid peroxidation. And what's interesting is that child GPT said this process is implicated in the pathogenesis of several diseases but as you will see it What it meant to say is several classes of diseases which basically covers almost all of the freaking diseases.

Cardiovascular Diseases and Lipid Peroxidation

00:05:24
chrisyzen
So we start with cardiovascular diseases, right? Lipid peroxidation plays a significant role in the development and progression of cardiovascular diseases, especially atherosclerosis. In this condition,
00:05:37
chrisyzen
low density lipoprotein LDL cholesterol undergoes oxidative modification becoming oxidized LDL which is then taken up by the macrophages forming form cells that contribute to the formation of atherosclerotic plaques and these plaques can lead to coronary artery disease stroke and myocardial infarction so it's not one disease it's a bunch of diseases and a huge portion of the population are likely to succumb to one of these cardiovascular diseases, something like a third of people. So it did downplay it a lot. There is still some bias, even though it's a very sort of objective thing that you can't cloud too much. Next is neurodegenerative diseases.

Neurodegenerative Diseases and Lipid Peroxidation

00:06:27
chrisyzen
Lipid peroxidation is heavily involved in the pathology of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. In Alzheimer's disease, lipid peroxidation products like 4-hydroxy-nonanol and melanodialdehyde accumulate in neurons causing oxidative damage to membranes, proteins, and DNA which impairs cognitive function and accelerates neuronal death. so So far we have cardiovascular diseases, neurodegenerative diseases, dementia, Alzheimer's, Parkinson's. Then we have cancer.

Cancer and Liver Diseases

00:07:00
chrisyzen
Oxidative stress driven by lipid peroxidation is a major factor in the the development of various cancers. Lipid peroxidation by products such as 4-HNE are highly reactive and can form DNA adducts leading to mutations that promote carcinogenesis. excuse me
00:07:17
chrisyzen
ah ah sneake
00:07:20
chrisyzen
sneeze so chronic cheese crush and its needs sorry about that
00:07:28
chrisyzen
very professional i know chronic oxidative damage to lipids proteins and DNA is a known contributor to the initiation and progression of cancers in tissues like the liver colon and breast then liver diseases lipid peroxidation is closely associated with liver conditions particularly none alcoholic fatty liver disease, NAFO-D, and alcoholic liver disease. In these conditions, oxidative stress leads to the accumulation of lipid peroxidation products contributing to liver cell injury, inflammation, and fibrosis, which can progress to non-alcoholic, steato, hepatitis, or NASH. So NAFO-D or non-alcoholic fatty liver disease, something like a quarter to a third of the American population
00:08:11
chrisyzen
have this, at least the adults, so huge. Then, chronic inflammatory diseases.

Chronic Inflammatory Diseases

00:08:18
chrisyzen
I mean, this is a huge sort of blanket term. So lipid peroxidation is a driver of chronic inflammation contributing to diseases such as rheumatoid arthritis, inflammatory bowel disease, and systemic lupus erythematosus, SLE. The oxidative stress generated by lipid peroxides amplifies the production of pro-inflammatory molecules like cytokines, leading to tissue damage and exacerbation of these autoimmune and inflammatory conditions. Then we have diabetes and metabolic syndrome. No, I thought it was the the carbs. My God, it's the the carbs doing it. Nope. So and carbs are a very small part of diabetes and metabolic syndrome, actually.
00:09:05
chrisyzen
as we've covered in previous episodes. So lipid peroxidation is also implicated in the development of type 2 diabetes and metabolic syndrome. Increased oxidative stress from lipid peroxidation contributes to insulin resistance, beta cell dysfunction, and chronic inflammation, all of which are hallmarks of diabetes. Furthermore, lipid peroxidation products may impair glucose uptake and promote complications like diabetic neuropathy and cardiovascular disease.
00:09:35
chrisyzen
kidney diseases is another one, respiratory diseases like chronic obstructive pulmonary disease, COPD and asthma. ah

Oxidative Damage Across Diseases

00:09:45
chrisyzen
Lipid peroxidation contributes to lung tissue damage and inflammation, oxidative stress, exacerbates, airway, remodeling, fibrosis and impaired lung function seen in these chronic respiratory conditions. And the conclusion is that lipid peroxidation is a key process that drives oxidative damage in a variety of diseases, including cardiovascular neurodegenerative disorders, cancer, and chronic inflammatory conditions. So pretty serious. Like I said, one of the primary
00:10:22
chrisyzen
drivers of Adrian dysfunction. This is this causes both oxidative stress and inflammation and damage just overall damage to cells, tissues, organs, organ systems, and then the organism in that order.
00:10:40
chrisyzen
And the more it goes out of sort of unchecked over the years and decades, the faster a human ages and and ah ah starts developing diagnosable diseases and conditions.

Causes of Lipid Peroxidation

00:10:53
chrisyzen
Now, the next question I asked Chad GPT was, which types of fatty acids are most prone to peroxidation?
00:11:06
chrisyzen
very
00:11:08
chrisyzen
you You can't lie, you can't have a roundabout answer here because it's it's very well known, just not really advertised. So polyunsaturated fatty acids are the most prone to lipid peroxidation. The high degree of unsaturation or multiple double bonds in these fatty acids makes them particularly vulnerable to oxidative damage. The more double bonds a fatty acid has,
00:11:36
chrisyzen
the more susceptible it is to being attacked by reactive oxygen species leading to peroxidation. Now, the omega-3 fatty acids are the longest. So, ecosopentanoic EPA and the cosohexanoic DHA both found in fish oils are highly unsaturated omega-3 fatty acids. DHA with six double bonds is especially susceptible to peroxidation. The double bonds in omega-3s make them prime targets for ah ROS leading to the formation of lipid peroxides and reactive aldehydes like malandaldehyde and 4-hydroxy, none at all. Then the omega-6 fatty acids, linoleic acid,
00:12:21
chrisyzen
which is the most abundant omega-6 fatty acids in the food supply and arachidonic acid are common omega-6 fatty acids and arachidonic acid in particular has four double bonds and is highly prone to peroxidation. This susceptibility plays a role in inflammatory conditions as the oxidation of arachidonic acid leads to the production of pro-inflammatory molecules. and ah ah And so that's the oxidation of arachidonic acid. But then there's also the anzymatic enzymatic
00:12:57
chrisyzen
transformation of arachidonic acid into various inflammatory molecules like prostaglandins and stuff like that. right So omega 3s and omega 6s are the most prone to oto peroxidation fatty acids. Then saturated fatty acids have no double bonds making it them much less susceptible to peroxidation and monounsaturated fatty acids such as oleic acid, which is found in olive oil, because they only have one double bond, hence the name mono. They're actually more resistant to oxidative damage than polyunsaturated fats, but still more susceptible than saturated fats. That's why I tell my clients, don't cook with olive oil if you can help it. But if i I was at a restaurant and
00:13:53
chrisyzen
they only had olive oil or sunflower oil I would tell them cook my thing in olive oil obviously. Now the third question I asked Chad GPT is what factors cause lipid peroxidation? You see if I had gone and asked the question does Omega 3s cause lipid peroxidation and whatever else? It it was going to start giving me these rather o Omega 3s are so good for you. But occasionally, and if if the stars in align, they may potentially cause some lipid peroxidation that could perhaps maybe be damaging.

Free Radicals and Lipid Peroxidation

00:14:34
chrisyzen
right But when we kind of ask very isolated questions, it can't really give us this sort of run around.
00:14:39
chrisyzen
So I asked, the third question I asked was, what factors cause lipid peroxidation? And this is where people need a little bit of education because people think, yeah, but I'm i'm healthy. So that that's fine. I can take my fish oil and I'll be fine because I'm healthy. I don't have a disease. I don't have a diagnosis of a disease. Therefore, you know, I'm healthy, but that's not reality.
00:15:09
chrisyzen
So lipid peroxidation, again, it occurs when free radicals or reactive oxygen species attack the polyunsaturated fatty acids, right the double bonds. That initiates a chain reaction of peroxidation reactions that leads to oxidative damage. And when you see the factors that actually trigger or accelerate this process, you will be you will understand what I'm talking about. So the first is, like I said, free radicals reactive oxygen species. So things like superoxide, anions, hydroxyl radicals, hydrogen peroxide. and So these are the primary culprits in initiating lipid peroxidation. So these reactive oxygen species,
00:15:57
chrisyzen
they, yes, they are caused by stressors and inflammation and toxins, but they're also caused their byproduct of just regular metabolic activities in the human, like when we we're producing energy by oxidizing or burning glucose, right? And obviously, if the mitochondria are dysfunctional in some way, if some nutrient in the pathway is missing, if there's a deficiency or there's toxins attacking certain enzymes or whatever, that that's greatly worsened. But we are still producing these just by regular energy production, regular metabolic processes. So you can't escape these free radicals, reactive oxygen species. It doesn't matter how healthy a human is, every single person on the planet

Light, UV Radiation, and Heat

00:16:49
chrisyzen
right now has some level of lipid peroxidation. The key is to do things so that we minimize it as much as possible. right The next thing is exposure to light and UV radiation. So light, especially ultraviolet light, accelerates the production of free radicals and enhances lipid peroxidation. So if you're eating a lot of Omega sixes from nuts or from restaurant food that has seed oils in it or processed food or takeout or whatever, or you're getting a lot of Omega threes. These will be incorporated in your tissues and that includes the skin right at the eyes and stuff like that. Right. So when those tissues are exposed to light, especially ultraviolet lights, we basically you go out in the sun.
00:17:40
chrisyzen
if you If you're loaded up on these polyunsaturated fats, including omega-3s, you are basically the exposed to this peroxidation, more so than someone that has less of these. Now the key is not to hide from the sun or to use sunscreen, I don't think, is to be obviously to be smart with when you're exposing yourself to the sun. That's critical.
00:18:04
chrisyzen
but also it's to get these things out of your body that takes years, but you really need to, if you haven't started that process, you really need to start that process now because it does take years. Then the other thing is heat and high temperatures.

Cooking Oils and Rancidity

00:18:20
chrisyzen
So we know that cooking oils,
00:18:24
chrisyzen
when they're heated they ah ah there's a bunch of these aldehydes and breakdown products, peroxidation breakdown products that are produced and then the food absorbs them right so when you're eating fries sorry to ruin it for you if you didn't know yet but when you're eating fries potato fries or whatever fried chicken, you are unfortunately ingesting a lot of these things that then deplete your antioxidants that then leaves you more vulnerable to peroxidation reaction because you have a lowered antioxidant status. So that's one thing but that you see that that that's just one thing and don't forget that when you buy if you've ever bought whatever
00:19:15
chrisyzen
polyunsaturated fat oil that could have been cod liver oil or something like almond do oil or walnut oil something fancy that they told you was cold pressed and organic and it's super awesome and super expensive you you would know if you bought this and you kept it in your fridge for a long enough time period it goes rancid even though your fridge is like seven times cooler than your body or your body is seven times or so
00:19:46
chrisyzen
hotter at least probably than your fridge so if it will go rancid in the the fridge do you think these these oils or these lipids are getting peroxidized when they're in your tissues just spontaneously yeah because you you're pretty warm you're a pretty warm creature as a mammal as a warm-blooded mammal so That's another thing that people have to understand.

Metals and Pollutants

00:20:14
chrisyzen
It doesn't matter how healthy you are Or how many antioxidants you take and whatnot you we are exposed to oxygen to heat to light Almost on a daily but on a daily basis really So there's nothing nothing is really standing in the way of the slippet peroxidation right and that's
00:20:38
chrisyzen
in in the perfect circumstances, but most people are not living in these optimal circumstances to begin with. Then we have other things like even just metals, nutrient metals in our body, like copper, iron, they can also cause lipid peroxidation. But that's again, that's in perfect conditions. But a lot of people nowadays, they're actually a little bit overloaded on iron because the at least the American food supplies heavily fortified with iron from cereals to whatever biscuits everything is like not everything but a lot of things are iron fortified so some folks have this iron overload that is contributing to this and then there's other metals toxic metals heavy metals that can also do this they can trigger this a bit peroxidation and a lot of folks they have an accumulation of these because
00:21:29
chrisyzen
just that's just the fact of the modern world but then there's also pesticides and industrial pollutants and air pollution a lot of these things again trigger lipid peroxidation okay and then there's a couple of other things so mitochondria dysfunction i kind of mentioned if you have an antioxidant deficiency which is actually fairly uh if you read my book discussed a little bit some studies on the vitamin E status of a lot of Americans. It's pretty low in general and just in terms of the world population has been some some research. So in general, people's antioxidant status is not very good.
00:22:11
chrisyzen
They're lot loaded up on these Omega-6s. Many people also have a lot of Omega-3s. They're supplementing a lot of Omega-3 fish oils. And again, these Omega-6s, they are substrate for inflammatory molecules in the body through the Lynn Lake acid or academic acid pathway. And that if that's left rampant, which ah for a lot of people it is, a lot of people have chronic low-grade inflammation.
00:22:38
chrisyzen
That is also associated with elevated reactive oxygen species levels and that also initiates lipid peroxidation. So there's a lot of factors here that basically I don't think i don't have to be I don't think you have to be a rocket scientist, rocket surgeon, or or a rocket surgeries to understand that the less omega 3s and omega 6s you have in your body, better.

Reducing Omega Intake

00:23:16
chrisyzen
that's that I don't think worrying about the deficiency
00:23:21
chrisyzen
It should even be like a matter of discussion, right? Am I going to be deficient in Omega-6s and Omega-3s? Especially Omega-6s are so prevalent in the food supply that I don't think we should even entertain the thought of all but I might become deficient if I don't supplement whatever or I don't eat enough of these oils or whatever no it's everything has them you know so I i don't I don't think it's it's worth worrying at all what we need to be worrying is how to get these things out of our diet and our life systematically and comprehensively yesterday last year really
00:24:03
chrisyzen
because again it takes multiple years for these things to get out of your body and while they're in your body unless you do the work that we do with my clients you are leaving yourself vulnerable to lipid peroxidation and with the metabolomics test that we run on clients now we can see the level of the lipid peroxides and often I'm seeing it in the yellow for clients that are already doing some stuff it's not like they're coming to me on the standard American diet and It's like oh my god.

Testing and Monitoring Lipid Peroxides

00:24:37
chrisyzen
I don't take any supplements. I'm meeting just you know McDonald's three times a day and My lipid peroxides are in the yellow. No, they're coming a lot of people are eating organic already or mostly organic They're taking multiple supplements sometimes a dozen sometimes two dozen or more and they're doing a lot of things and they're actually listening to health podcasts or they're doing a lot of stuff yet, they're still a
00:24:59
chrisyzen
They're lipid peroxides and sometimes there's a marker for DNA damage. We also check on on that metabolomics test, which is just a simple urine collection. You take it home and the courier comes and picks it up. So couldn't really couldn't be any more convenient than that, you know. And so what we also do with that one is there's an add-on. It's like 50 bucks, like I've said before, for the Omega 3 or for the just for the fatty acids in general.
00:25:26
chrisyzen
which is a little blood spot, you just prick your finger, drop some blood on on a piece of paper, and you ship that off with the urine sample. Super convenient, right? And then, so what we can do is we can look at the level of like lipid peroxides, at the oxidative stress markers that includes the DNA damage marker I mentioned, 8OHTG, and then we can compare that with the omega 3s, omega 6s, what's the sort of the levels of the various fatty acids in the in the blood at that time, and I think I mentioned it last time when I went when i was discussing omega-3-c, I'm starting to notice a pattern when the lipid peroxides are in the yellow, somewhat elevated.
00:26:09
chrisyzen
the omega-3s tend to be low or even in the red so quote-unquote deficient and that is such a such a strong signal that it's the omega-3s that are the first to peroxidize right so it could be it maybe you have a lot of omega-6s in the in the tissues in the body and it could be like some omega-6s that get peroxidized so they're the the the initial spark that causes this chain reaction and lipid peroxidation. But if you have a lot of omega-3s in the body,
00:26:43
chrisyzen
then they are super easy to peroxidize because they're so unsaturated, so vulnerable, so many places that can be attacked, you know, quote unquote, by these peroxidation reactions, reactive oxygen species and other various free radicals, right? So it's such a, this test, the the metabolomics test,
00:27:08
chrisyzen
Because we test for so many things including detoxification capacity and fungal stuff and gut stuff and various vitamin deficiencies, various sort of enzymatic blockages in the body, right? It's such a wide-ranging snapshot of the metabolism that to me it's it's an absolute no-brainer of an investment of a few hundred bucks for the test because would you prefer to invest you know a few hundred bucks for a test that tells you some stuff that then we can correct?
00:27:46
chrisyzen
Or would you prefer to go for the next 10, 20 years with like some, ah ah not super high, but a little bit of the but too much lipid peroxidation, just in the yellow, not in the red, a little bit of too much DNA damage, not in the green, just in the yellow, you know, and various vitamin and mineral deficiencies and potentially not knowing if you're getting acute toxic metal exposure. These are the kind of clues that we can glean with one simple little urine collection, you know, and a little blood spot test for the fatty acids. So imagine catching something like this 20 years early because most people won't. Most people will continue on their merry way.

Does Aging Lead to Disease?

00:28:27
chrisyzen
They will you know invest their money instead of you know supplementation and organic food and lab tests to kind of look after themselves and working with like a
00:28:39
chrisyzen
ah ah health coach or a practitioner they will go on a vacation with that cash that maybe they'll get another car or they upgrade their car or they'll get like a fancy new device the newest iphone or new tv whatever the case may be right so the problem is they won't catch or address these things decades before they become a problem for them. So then they might you know turn 60 or 70 or whatever and go to the doctor with a lot of health issues, get diagnosed, get their various pills and poisons. And the doctor will say, you know, that's a part of getting older. it's what What can you do? It's genetic. And no, it wasn't. it's not It's not a requirement. It's not a feature of aging to develop disease because
00:29:34
chrisyzen
We know lots of old folks that are in their 80s still and they don't have any diseases. So if they can go get to that age without developing disease, anybody can.

Early Intervention and Continuous Monitoring

00:29:48
chrisyzen
This genetic stuff is a cop-out. It's a part of aging is nonsense. Even in old age, even people in their 70s with a couple of supplements, you can improve a lot of these inflammatory markers. and mitochondria dysfunction or antioxidant deficiencies and oxidative stress even in old age. so But why wait until old age? Why wait until you or do you have the the the problem before you actually preempt and kind of fill up the crack in the dam, fix the crack
00:30:21
chrisyzen
way upstream decades or years before an actual issue is felt in your body you know so that's all we can do and it's it it really couldn't get any more convenient than it is nowadays you know the the the test gets shipped to your door collect it at home call the courier they can't pick it up or you can drop it off on the way to work or whatever if you're out and about And that's it, you know, then we just wait, wait a little bit for the test results. There's nothing else that that needs to be done, you know. So it's a it's a great time to be alive in some ways. We have and then we have all this access to these really awesome supplements that can correct any deficiencies and issues, oxidative stress, inflammation, all that stuff. So on that ah sort of side of the coin, we are lucky. But then on the other side of the coin, we are a little bit unlucky is because
00:31:19
chrisyzen
these are Omega-6s and, you know, seed oils and potent saturated fats, they permeate the food supply so much. And the all the pollution we are breathing in on a daily basis, that's contributing to oxidative stress, lipid peroxidation, inflammation, all that stuff. So there's a lot of issues in the modern environment, but that's that that's that means that These things are no longer a luxury because these things are all so affordable. The lab testing, the supplementation, all that stuff. It's so accessible. It's so affordable that I don't think it should be a a luxury, considered a luxury. It should be considered mandatory to survive and thrive in the normal world because surviving is not that hard. You can easily survive to the age of 70, even 80.
00:32:10
chrisyzen
without doing much. But the there's a high chance that the last few or 10 years of your life might be fairly horrific in terms of if you have to battle a chronic condition and stuff like that. right So that's not thriving. That's just degenerating for 10 years before. you know the end, which sucks. that's that's I personally don't don't want that for myself or anybody I know. So the key is to make what was once deemed a luxury, to make that a priority, right? A non-negotiable. For me, supplementation now and organic food, for example, you not not not that organic, at least in Europe it's still good, but in the USA organic food is not
00:32:55
chrisyzen
necessarily the endo bill or anything but quality food is non-negotiable it should be non-negotiable for anyone that wants to not just survive but thrive in the modern world and then supplementation as well that should be non-negotiable and then if a person has a health issue or is not ah ah at an optimal state of health then they absolutely should make it a non-negotiable to invest in either a good practitioner, lab testing or some kind of combination of that, a health coach, whatever the case may be, whatever helps you improve your state of health until you're thriving.

Conclusion: Prioritizing Health

00:33:34
chrisyzen
I think those things should be non-negotiable, the supplementation, the lab testing, stuff like that. Because how else, without gathering down on yourself, how else are you going to figure out what the heck is wrong and and what what to to work on? you know This sort of, oh, it's genetics, I'm getting old, that's why. No, that's bullshit. That is absolute bullshit.
00:33:55
chrisyzen
It's just a cop-out by the medical industry for not knowing how to not not knowing or not wanting to actually help people heal, just so they can be managed with pharmaceuticals and surgeries and stuff like that. you know It's a cop-out.
00:34:13
chrisyzen
It's an absolute cop-out and there's a lot of money being made on the back end of that. So it's it's at least at this point it's a choice people are making, right? Because the solutions are out there, you know? Anyway, what the hell was I talking about? I forgot but what I was even talking about.
00:34:29
chrisyzen
got a bit ranty there near at the end and anyway thank you for listening tuning in and i will see you on the next episode i hope you found this interesting and it made you rethink some things you may be doing on a daily basis because unless those things change those habits in microhabits and habits, unless they change and are sort of shifted over time, we we don't change trajectory and that usually for most people nowadays, it's a trajectory of poor health, diminished longevity, and the eventual development of disease. So only you know how and how to steer that ship a few degrees.
00:35:07
chrisyzen
in a different direction. And if that's the case for you, you know there's lots there's lots to work on just based on today's episode. So get at it. And I'll see you on the next episode. Thank you for listening.