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How to Use GLP-1s to Extend Your Life with Jay Campbell - E96
39 Plays12 days ago
Why are GLP-1s dominating the health conversation right now, and why are so many people still getting them wrong? What if the real issue isn’t the medication itself, but how we understand and use it?
Learn why framing GLPs as a “quick fix” misses the bigger picture, and how using them as a tool - not a solution - can unlock real, sustainable change.
In this episode, we explore the science of GLPs and peptides through a more grounded lens, breaking down how they impact appetite, metabolism, and even behaviour. You’ll learn why most people misuse these compounds, the critical role of dosing and lifestyle, how “food noise” is wired into the brain, the difference between short-term weight loss and long-term healthspan, practical ways to integrate GLPs responsibly, and how to build a foundation that actually lasts.
Jay Campbell is a health optimization pioneer, five-time international bestselling author, and one of the most respected voices in peptides, hormone optimization, and human longevity. As co-founder of ‘BioLongevity Labs’—the rapidly emerging peptide and bioregulator powerhouse known as the Amazon for biohackers—Jay has spent more than two decades pushing the frontier of metabolic health and anti-aging science.
“Their brains are wired to eat because they have been poisoned brain pattern wise from these food scientists and these chemicals.” - Jay Campbell
In this episode you will learn:
- What peptides are and how they target the root of health issues.
- How healing peptides like BPC and TB500 can speed up recovery from injuries.
- Why GLP peptides are a breakthrough for fat loss and breaking habits tied to cravings.
- The key steps for safe and effective use of GLPs and growth hormone peptides.
- How to match peptides, blends, and cycles to your health goals.
- Tips for starting with the basics and using new tools as part of a bigger plan.
Resources
- Connect with Jay on X: https://x.com/JayCampbell333
- Watch his YouTube channel: https://www.youtube.com/@jaycampbell333
- Learn more about his offerings: https://jaycampbell.com/
This podcast was produced by the team at Zapods Podcast Agency:
https://www.zapods.com
Find the products, practices, and routines discussed on the Alively website:
https://alively.com
Recommended
Transcript
Introduction to Home of Healthspan Podcast
00:00:00
Speaker
The food scientists that all these giant agro corporations spend billions of dollars every year in creating these chemicals to addict people. The GOP attacks those sensations in the brain and rewires pathways so that these people are not sitting there as a slave to eating.
00:00:23
Speaker
This is the Home of Healthspan podcast, where we profile health and wellness role models, sharing their stories and the tools, practices, and routines they use to live a lively life.
00:00:36
Speaker
All right, listeners the Home of Healthspan podcast. This is a very timely, very relevant, very hot topic
Introduction to Jay Campbell and His Mission
00:00:43
Speaker
right now. And I could not be more excited for our guest today, Jay Campbell.
00:00:47
Speaker
Jay, thank you for joining us. Andrew, thank you for having me. I'm always humbled and privileged and honored to be speaking about the things that I love. And, you know, as you know, and I know you would agree with me, I really think that the stuff that I'm involved in right now is really kind of the make or break as we move forward into what I call quantum healing, right? Because I think sick care slash allopathic medicine is
The Promise of Peptides and the Fall of Traditional Medicine
00:01:09
Speaker
collapsing around us. And so now it's time for people like you and I and the people that are in our circles to really influence and lead from the front and talk about these amazing revolutionary compounds like peptides, bioregulators, and small molecules.
00:01:21
Speaker
Millions of lives have already been absolutely transformed in the past few years from it. And I do think it's the tip of the iceberg where we're going. But before we dive into that and everything you're doing, how would you describe yourself, Jay?
00:01:33
Speaker
I would describe myself as a very, very deep, resonant thinker who truly is on a mission to save. i shouldn't say save to help people um become the proactive scientists of their own health.
00:01:48
Speaker
Yeah, I love that. Because we're all in of ones, you can kind of learn a lot from research at a population level. But if you're in the 20% as opposed to the 80%, different things are going to resonate. So for us to all live lively lives, we got to take the reins, right?
00:02:05
Speaker
A hundred percent. Yeah. You've got to be, as I say, you have to become empowered, sovereign and free, you know, of, you know, the external or externalizing your power. Right. So that's how you become that. And obviously in our space, in the healthcare space, you can't go to your garden variety, general practitioner, or family doctor and ask them how to let you live to 150.
Empowerment Through Health Responsibility
00:02:25
Speaker
Right. You got to take that initiative, you know, upon yourself and you have to learn, you know, through podcasts like this, through, you know, information like this.
00:02:33
Speaker
how to do this yourself. and And that's why I like to say, become the proactive scientist of your own health, because there's nobody else out there going through your medical records, you know, attempting to give you insights on how you can live longer and stronger. So it's all, it's totally up to you.
00:02:46
Speaker
Yeah. And on that, I mean, I think, We could go many, many different directions because
Peptides: Evolution and Potential
00:02:52
Speaker
there's a lot to do. But if we could go super deep, as deep as we can on peptides, I think it's something people have heard a lot about.
00:03:00
Speaker
It's a wide range from, hey, I have my vitality, vital proteins, collagen peptides, right? Like I scoop it in my coffee versus GLP-1s and then these more performance ones. So probably if people are aware of the topic,
00:03:16
Speaker
They've been introduced to it through GLP-1s. And you actually have an upcoming book very specific to GLP-1s. So maybe could you first just define what the space of peptides is? And then maybe we'll go through different categories and and usages.
00:03:32
Speaker
So I'm in a big documentary. It's actually a series. It's probably coming out. We don't know, either late, late this year or early next year. It's called Peptide Society. You're either in or aging out.
00:03:43
Speaker
And it's got a lot of amazing like early adopters, you know, call them real OGs, you know, that are actually in this space before anybody even knew what a peptide was. Right. So I think you know this, but I'm sure your audience does it. Like I've actually been using therapeutic peptides since 2003, which was like four years after I started using therapeutic hormones.
00:04:04
Speaker
so I was like you know in the real trenches, um like I like to say, when the signal-to-noise ratio on the internet was actually mostly signal and very little noise. and As you and I know now today, it's the complete opposite. but Very, very truthfully, 1%... This is all from the pop you know the the research that the documentary folks in Hollywood did. Only 1% of the global public even knows what a peptide is.
00:04:28
Speaker
So when I say that, you know, we truly are in a ocean or, you know, deep blue ocean opportunity because you and we live in, you know, call it the transformational aspect of functional health and medicine and stuff like that. And so everybody that we talk about is all talking about peptides. Right. And when we go on social media, we get behaviorally targeted by all the peptide people and stuff. But it's such a small percentage of the world. Right. So truly, this opportunity is the biggest opportunity in all of health, because, as you know, for people and for people that don't, you know, peptides treat and address the fundamental root cause.
00:05:04
Speaker
of illness, disease, dysregulation, right? So like if we understand how to use a peptide therapeutically, we can actually, you know, really live longer, as I like to say, live leaner longer, right? And that's kind of like the goal. And there's so many different peptides. There's, I think right now, 57 commercially available.
00:05:22
Speaker
But as you and I both know, there's thousands that have been identified in science. They're just not made yet. So We really are at the tip of the iceberg. We're truly in the infancy of peptides. I would say over the next three to five years, if we can just get the 1% to 5%, we'll make a gigantic, titanic, almost astonishing level of transformation.
Personal Stories and Ethical Dilemmas in Peptide Use
00:05:43
Speaker
Because like you said, millions of people have already had their lives transformed. Every single day, Andrew, I get messages from people about using BPC and TB500, right? Or using Cardilax and BPC and TB500 or stuff like that. and they're like, why do not, why do not more people know about this?
00:06:00
Speaker
Look, I'm in this space, right? I'm in this space. And for two years, I got out of a swim, slipped on the rocks, fell on my shoulder. And for two years, i couldn't really lift my arm above my shoulder. I couldn't do an inclined bench, just in pain, couldn't sleep on my right side.
00:06:17
Speaker
And doctor, people kept saying, you need to try BPC. People at the gym, you need to try BPC. It took me two years. And within five days, my arm was just fine. And I'm sleeping. I didn't need to go through this for two years. And so that's when I said, okay, this is a very, very interesting world that,
00:06:36
Speaker
I met with a lot of orthopedic surgeons, got MRIs, but five days of BPC and life was transformed. You know, I talk about that all the time and I have some of the, some of the best orthopedic orthopedics in the world are my friends, right? and Talk to them all the time. And it's a crisis of conscious for them now, right? Because they used to order, you know, $120,000 exploratory, you know, repair surgeries, ACL, MCL, PCL reconstructions, you know, shoulder reconstructions, et cetera.
00:07:05
Speaker
And if you've got a 50-year-old plus or a 45-year-old plus aging patient now, we ah they know, at least the smart ones know, that they could give them, you know, BPC and TB500 for $600. You know what i mean? and and And they could do that for, you know, six to eight weeks versus this surgery, which they bill a lot more money and, you know, through the insurance segregation. So it's a really weird problem.
00:07:26
Speaker
There's risk on the surgery, too. I mean, I had a friend go in for foot surgery who's dead now, right? A guy I went to law school with. So if you get, dude, don't even get me going about invasive surgeries, but the truth is, is that a 50 year old man or woman, whether they were ex pro athlete or not having a replacement or a repair,
00:07:45
Speaker
is the tensile strength of the tendon and the ligament is not the same as if they were 18 or 20, right? So like, even if you graft it, replace it, repair it, whatever, you're unlikely to get the same value than you would if you just injected BPC, TB500, and cartilax into the area for six to eight weeks from a repair standpoint. And obviously it's far less invasive and it's far cheaper.
00:08:08
Speaker
So it's just one of those weird times where, you know, those guys, meaning the orthopedic surgeons, It's a hard thing for them, right? Because they make so much money doing the surgery and they obviously have been trained and conditioned to recommend surgeries. yeah I always say, if you go to a surgeon and you ask them, hey, do you think I should do this? what do you think they're going to say? No.
00:08:26
Speaker
I mean, some of them actually do, but I mean, come on. At the end of the day, it's difficult for a surgeon to do either or. And I've spoken to some of these folks. And again, I won't mention names, but it's a crisis of conscience for them because they're like, how do I continue when I know what BPC and TB500 will do? I know what you know KPV and BPC and TB500 and GHKCU and all these amazing healing peptides will do versus having this surgery. And then let's not forget, Andrew, I mean, the surgery, you know, you're now three to six to nine to 12 months of healing.
00:08:57
Speaker
Yeah. Right. And and that's, and what we've learned on aging and decrepitude, it's not a slow, slow down. It is you have that surgery and you can't move.
00:09:09
Speaker
so we're saying Before we we go too deep, I mean, let's, let's maybe think about categories as we talk through
Understanding Peptides: Benefits and Administration
00:09:15
Speaker
these. So we started because of the story of BBC with kind of muscle and tissue repair.
00:09:23
Speaker
And so the whole BBC world, TB5 world, cartilax, like, Could we cover what that is, right? What is BPC, the stomach acid, et cetera? What are these used for When would you think to do it? What cycling looks like? let's Let's tackle that as a category and then maybe we can go through some other things.
00:09:40
Speaker
Yeah, no, for sure. And that's actually a good idea to do it because I think it's important to say this. A lot of people, when they first you know become aware or knowledgeable about peptides, they have you know the shiny things syndrome.
00:09:51
Speaker
And it's like, oh my God, I want to do this. I want to do this. I want to do this. I want to do And then they want to take 10 peptides at once and not really address the biggest issue. And so... I really like to say it's kind of the bleeding neck issue with peptides. Like what is your biggest issue that you need to solve for, right? Most people in America today are metabolically dysregulated, too much visceral fat, et cetera. So it's like, let's lose some fat. Let's clean up our metabolic machinery. But to your question around healing, and we can go through obviously various stages of, again, levels of peptides, but for
00:10:22
Speaker
For healing, BPC-157 is a peptide that's found naturally secreted in human gastric juice. and It increases when you inject it. and By the way, we should say this, the the highest impact delivery system for most peptides is injectable. right It's two reasons. It crosses the blood-brain barrier the fastest, and then second, it gets into portal circulation also the fastest, which obviously from an absorption standpoint and systemic level, you want that. but There are peptides that can be also used inter intranasally. They can be used transdermally. They can also be orally consumed.
00:10:58
Speaker
The delivery systems on peptides are really advancing, right? There's new micron strips. And so they're like 20 to 30 to 40 tiny little microscopic needles that you can literally just slap on a Velco strip on the arm.
00:11:12
Speaker
And some of the peptides are small enough that they can be delivered with these needles. But these are improving. And when these are up to like 60 80, you'll probably be able to use almost any peptide. So the good news is for people who are afraid of needles, which is 80% by the way of society, the delivery systems are improving. But back to your original question, um I would say the four primary, and there's probably six, but the four most well-known peptides for healing are what we said, BPC-157, which again stands for body protective compound, Thymus and Beta 500, which TB-500,
00:11:46
Speaker
Both of those peptides are usually found together in blends, which are you know usually known as the Wolverine blend because as BPC improves angiogenesis and you know regrowth or tissue signaling, fibrosin beta suppresses inflammation.
00:11:59
Speaker
So they're really, really powerful when used combined, especially injected at the origin in the injury when it's especially like a soft tissue sprain or a strain or even a ligament tear.
00:12:10
Speaker
And then the other ones to mention, like copper peptide GHKCU is also very powerful in increasing angiogenesis. It also does a lot of stuff from a cosmetic standpoint in that it reduces fine lines and wrinkles.
00:12:22
Speaker
It increases, um again, angiogenesis in the sit in in the cellular cascades, in the face, and in soft tissue. And then I would also mention Cardilax because you mentioned it. Cardilax is a very powerful Russian bioregulator. It is injected and it has this, it's almost mysterious, but it has a way to actually help rebuild cartilage. So if you inject Cardilax in person with low back, severe inflammation, you know, disc compression, spinal compression,
00:12:50
Speaker
They're not going to get healing, obviously, depending on how close they are to the bone, but they get a lot of symptomology relief from a pain and inflammation standpoint. So that's really good. My company, BioLongevity Labs, sells a blend called Regeno, it's BPC-157, TB-500, and Cardilax. And that, by far and away, is the strongest healing blend of injectable products. I put that up against Clo or Glow, which is obviously... Clo is KPV, GHKCU, BPC and TB-500, and then Clo That's a glow versus glow. Yeah.
00:13:22
Speaker
and Right. It's KPV versus GHKCU in the four. Yeah, we actually, my social media team just did this giant thread about the difference between the two and how people should use them. And and we really just, the science shows that the difference between glow and glow is if you're, if you have severe autoimmune dysregulation, you probably want to use glow because of the KPV.
00:13:44
Speaker
versus glow would be like, you know, uh, you know, uh, anti-aging, uh, you know, improving fine lines and wrinkles, uh, collagen production, et cetera. In the face, my wife actually uses a pen and she injects glow, uh, in the face. Right. With a little four inch micron needle. So she injects it like right here. A lot of women do. There's tons of people, you know, in the aesthetic and beauty space that inject those. But you can also use a very powerful like transdermal formulation of GHKCU by itself, like three to so three to five percent grade.
00:14:16
Speaker
And, you know, you got to use kind of a topical because if if it's transdermal, it can actually burn the skin. You got to be really hardcore, man. And harsh if you want to use like a four or 5% grade of GHKU on the face. I mean, it works, but it burns.
00:14:30
Speaker
Right. So I do know women that actually do that because obviously, you know, their face looking young as they get older is so important to them. But I think moving on from healing, we probably should talk a little bit about fat loss and muscle building. Yeah, let let's cycle back to that. So like you said, that's that's the 80-20. That's most people metabolically dysfunctional in this country.
GLP Peptides: Innovations and Critiques
00:14:51
Speaker
So you would look at, in my opinion, you look at GLPs first, right? So obviously the three primary GLP peptides, and by the way, there are hundreds, and I write about them in my book and that in the chapter about what's in the pipeline coming.
00:15:05
Speaker
And what's amazing, Andrew, is like, I say this at the very beginning and the end of the book, in the summary, I say... What I recommend in this book now in two years may be irrelevant. That is how fast this call it golden age or biomedical renaissance is happening with all these amazing chemicals and call them small molecules that are coming into the marketplace to do all these amazing revolutionary things for the metabolism, for brainwave patterning, et cetera.
00:15:30
Speaker
But the three primary ones that most people know about are of course, semaglutide, which is known as Wagovi, which is Norvo Nordisk's product. To me, that's an irrelevant product at this point, even though there are millions of people that get scripts of Wagovi. You know, Trump Rx just came out on Friday. And so they got big ads everywhere. And it shows like how much they've lowered the price for, you know, negotiating through the federal government. But I think that's a completely worthless peptide. And i actually talk about it in the book because...
00:15:58
Speaker
we're so much farther advanced now than just appetite suppression. When you have GLP-2, which obviously increases glucagen expression or or signaling, and then you also have GLP-3, which is appetite suppression, glucagen stimulation, and metabolic upregulation, and improved nutrient partition and insulin signaling. So,
00:16:17
Speaker
it's kind of a crude, you know, peptide pathway and that you're just suppressing appetite. I think a lot of people too, who have taken, again, call it Wigovi slash semaglutide, you know, get that nauseous feeling. And by the way, I should just say this right now. um The book completely proves that GLPs,
00:16:36
Speaker
are the greatest inventions in the history of medicine. And why i say that is because 95% of people who have experienced, this is sad, but you know this to be true, 95% of people who have used GLPs have done them incorrectly. They have started with way too high of a dose and then they have not changed their lifestyle, which as you know, is also, ah you know, a lot of blame goes to a lot of the physicians who are prescribing them because they're not giving these people the lifestyle changes that have to be, you know, the epigenetic things that must happen to make them work.
00:17:06
Speaker
ah But also, it's also just because the pharmaceutical industry wants people to start at outrageous high-level dosages. And we know why that is, right? That's how they make money. yeah That's how the doc makes money. That's how the format that's all the pharmaceutical company makes money. That's how the pharma rep makes money. So it's all this insanity. And so all of these people who have had these horrible experiences with JLPs... Because, again, they started high, went higher, and then they didn't change their lifestyle. Because, Andrew, let's just be honest. If someone starts at a super high level dose of, let's just say, semaglutide GLP-1 or even terzapatide, which is manjoro or zepbound of GLP-2, some of these people don't eat for four days, right? They've completely whacked out.
00:17:47
Speaker
how everything from a cell you know a signaling standpoint in their body and they weight comes off because they're not eating and they actually think it's great and then as you know in two weeks when they haven't eaten any protein and they haven't done anything right they're not lifting weights everything unravels right metabolic haywire thyroid dysfunction hair falls out face collapses butt collapses all the stuff that we hear about in the mainstream news all true all completely avoidable Yeah.
00:18:14
Speaker
We go be face and all that. Yeah. it But it's completely avoidable. And so like, you know, we say in the book that the number one thing is number one is understand that your dosing does not have to be so high. Most people who understand how to use GLPs now use these things in a very surgically precise, call micro dose. And by the way, everyone can be micro dosed. It doesn't matter if the person's 400 pounds.
00:18:41
Speaker
Could I ask on that? Because obviously the the prescriptions come and if you're diabetic, et cetera, right? You can get interns to pay for it. But I'm hearing more and more from real doctors and scientists saying, look, this may be a magic drug a microdosing for everybody, what it does to insulin resistant, all these different. A hundred percent, everyone should microdose.
00:19:02
Speaker
Now, again, they don't say this because in the studies, they're giving them insane boluses. But you have to also understand that all of these people in the studies, not all of them, thank God,
00:19:14
Speaker
And that's what made the book so awesome is we found the studies where they actually did right the right things. But most of these people are not exercising. They're not changing their lifestyle. They're not living insulin controlled. They're not lifting weights. And all of them are not controlling for hormonal optimization.
00:19:30
Speaker
right So if you're going to use GLP, there's I have really 10 commandments, but in the book, we just say there's four things that have to happen. Number one is, you got without question, you have to microdose. and When I say microdose, there's this kind of a so ah sliding rule of thumb. you know If you're 400 pounds versus woman that wants to get down You know, your dose is going to be a little bit, you know, controlled for more appetite suppression, more strong stronger insulin signaling, et cetera, depending on if you're using GLP two or three. And then most important is obviously we have to eat enough protein.
00:20:09
Speaker
OK, we cannot take these very powerful metabolic, you know, improving regulation and appetite suppression drugs and not eat enough protein because you will lose muscle. It's 100% true. That's how powerful the drugs are.
00:20:21
Speaker
So we got to eat enough protein. And then we 100% also have to lift weights. Now, you don't have to lift weights. You could do, you know, hot Pilates, but it's got to be bone bearing resistance type training so that you can prevent, you know, atrophy, muscle loss, catabolism, et cetera. Those are very, very important and critically important. And then I would also say, and this is probably number one,
00:20:45
Speaker
If you're hormonally dysregulated, which I think we both know it's 80% of most people in America at this point because they're not testing for this. And the average you know doctor, again, GP family doctor has no clue. They're not taught about this in medical school. there's no standard care practice. So it's like if you're hormonally dysregulated and you start a high dose of any GLP, you are looking at nightmare coming, right? And this is what happens to the majority of
The Impact of GLPs on Lifestyle and Brain Health
00:21:11
Speaker
people. So eat enough protein, lift weights,
00:21:14
Speaker
Make sure that your hormone is at least balanced. I mean, I would obviously stress for optimization, but those are the real critical rules of thumb. And every person who is doing that and then uses these things, obviously we left off the you know microdosing, has tremendously profound transformational results. I have a chapter in the book called The Transformations. And it's 16 men and women from all over the world in all walks of life They're for and afters. I mean, I have pictures of 400 pound guys, 180 pounds with six packs. I have the same thing, 260 pound women who are 127 pounds with a six pack. But they did the work. They didn't just take the the shot. They did the work.
00:21:54
Speaker
Exactly. the The best part about the transformations is not the physical change. It's the words of these people and how this completely revolutionized their life. And they say it, every one of them, and they say it in different ways, but every one of them says without the GLP, this could never have happened. And that's what people really have to understand. And look, I'm not a shill for GLPs. I mean, I'm a shill as you are for lifestyle change.
00:22:21
Speaker
That's the only lasting way yeah to shift our lives. Right. But these drugs, when used precisely, allow this to happen to anyone.
00:22:32
Speaker
this works So I'll give an example. My father, my father was a pediatric cardiologist, 40 years, right? This is his job. This is what he did. And it didn't enter through the GLP-1s. It was the slow carb diet from Tim Ferriss.
00:22:45
Speaker
And he is said, I just had to unlearn what they taught me, which they taught me very little in medical school about nutrition. He lost 65 pounds in a year and started running half marathons. And now he sees himself as a runner. He goes and runs the Peachtree every year wearing his high school bib because it's real fits him now. That's awesome. After all that. And he didn't he didn't need the GLP as the spark, right? He was able, reading this book, to get his own spark and move.
00:23:09
Speaker
But he did the work, right? It wasn't exactly. Hey, I just do this. No, I'm going to run because once he took off the weight, it was more fun to move. He slept better because he he didn't have apnea. Like all these things start compounding around each other. And so if you use it as a spark, not the book, in not the end of the story. It's a tool.
00:23:28
Speaker
It's a tiny tool. And it's the greatest tool in the history of medicine, or I should say healing, quantum healing, because but like you said, some of these people in this country, especially let's just say the West,
00:23:41
Speaker
or you know They have the addiction to the hyper-palatability of foods, right? The food scientists that all these you know giant agro-corporations spend billions of dollars every year in creating these chemicals to addict people, to make them overeat.
00:23:55
Speaker
The GLP attacks those sensations in the brain and rewires dopaminergic, dendritic, and serotonergic pathways so that these people are not sitting there, Andrew, as a slave to eating every two and a half or three hours. That's what you know obese people, we really have to be supremely empathetic and compassionate because we don't realize that they have an addiction. Their brain is wired, as you said earlier in the show, biochemical individuality. Their brains are wired to eat.
00:24:28
Speaker
because they have been poisoned brain pattern wise from these food scientists and these chemicals. And again, I'm not making excuses for them, but a lot of them, it's very difficult to overcome that noise. And the GLP attacks the noise.
00:24:43
Speaker
All of these people in the transformation chapter talk about how they were finally able to find something that made them not think about food. And actually, and this is what's so insane, encourages them to entertain and maintain, and maintain which is most important, productive habits.
00:25:03
Speaker
Because as you know, or you probably know, the studies are showing that it's curing alcoholism. Gambling. It's curing obsession. Exactly. obsessive compulsive disorders. It's insane. and And why these people in the mainstream news are attacking these things without knowing that. I mean, I have a whole chapter, right? I had to do this. I had to address like all the celebrity mainstream doctors and the influencers and the subject matter experts that are attacking these things that have no earthly idea what they're talking about. They literally have no idea what they're talking about. It's it's shameful. I've had so many A-list people
00:25:40
Speaker
who have been introduced to me from other people who are like, before you shit all over GLPs, you need to talk to Jay Campbell, right? And this was before I did this book. So I'm so awesomely grateful this book is finally coming out here now because this will be the calling card to teach people that like, do not shame anyone, A, using a GLP or yourself shaming GLPs until you truly understand what the science shows about these drugs. And look, dude, there's a reason that Eli Lilly is a trillion dollar company now.
00:26:10
Speaker
It's not because of all the other drugs. It's literally because of terzapatide. And imagine where it's going when retitrutide is approved this year. Bro, retitrutide is the greatest drug in the history of pharmaceutical interventions. And I will stand behind that until the next thing comes because there'll be a stage four and a stage five coming, right?
00:26:32
Speaker
You'll have myostatin inhibitors. We already have a product that's a myostatin inhibitor right now that might even get bought out for a B word, you know, pretty soon because we have companies lining up to see the trial data.
00:26:44
Speaker
So, I mean, we're just in this, like I said, we're in a biochemical revolution and it's really on the consumer or the patient to become educated on how to use these things correctly because it's really easy to use them incorrectly.
00:26:59
Speaker
Yeah. And they're a piece of the puzzle. Maybe that first spark, the light, the kindling to go build this fire that is the burning fire of your life. Look, the foundational principles never change, right? Live insulin controlled.
00:27:12
Speaker
Make sure that you're not functioning with a hormonal imbalance. If you're 35, 45, 55 years old and you have a hormonal deficiency, it's really, really hard to live lean, to live longer, right? So address that. You can do it naturally. It's harder. It's becoming harder and harder to do it naturally. But obviously, therapeutic testosterone for both men and women is the biggest tool in the tool belt. And it's a transformational thing when done correctly.
00:27:35
Speaker
And then obviously, as you know, lift weights, do cardio, right? It's really simple. Build muscle. The longer I always say this to people, the longer you will live statistically proves based on how lean you are.
00:27:48
Speaker
So it's like if you are lean, you look at all those blue zone studies and all the octogenarian people, they're all lean.
Foundational Health Practices and Growth Hormone Peptides
00:27:54
Speaker
They have no inflammation. right? They don't have fat. You don't see obese people in senior citizens places. They just don't live that long because of cellular inflammation. So if you want to be lean and live long, you have to build muscle.
00:28:10
Speaker
And obviously you also have to do cardiovascular because we have to strengthen the vasculature as we get older. So those four principles can never be overcome. Peptides are great. GOPs are great. Therapeutic testosterone is great. They're just tools.
00:28:22
Speaker
That's all they are. You have to have the foundational precepts and in in place. Okay. So I think we've, we've done a good dive on the repair side, kind of the intro there on the, the weight loss side, the GLPs. Can we talk a little bit on maybe the, the growth hormone side? So sure simulation of that, whether it's some moreland, Tessa Moreland CJC with or without back kind of take us through that space.
00:28:51
Speaker
Let's just call them GH agonist peptides. right so the The strongest thing, obviously, is human growth hormone. right and I think human growth hormone is really very misunderstood. If we go back and we look at all of the longevity clinics, like the are old school people that were in the Life Extension Foundation,
00:29:09
Speaker
You see some of these people have been using growth hormone since the mid nineties and they've been using it in very, very, again, here we go. Microdose boluses of like one I use for women, 1.5 to two I use for men. And they've been using this and these people have, profound i would i call it biomarkers you know into their 60s, 70s, and 80s.
00:29:30
Speaker
There's you know always been this scare scare that if you use human growth hormone, that it could exacerbate you know metastatic tumors. or you know it it does stuff with mTOR signaling and stuff. but Here's why I know that that's mostly BS. If you look at all the research that people have done in dwarfs who take 25 to 30 IUs of human growth hormone a day, there's never ever been one single case in any of the peer review and published literature of a cancer that occurred in any of those people. So when you then extrapolate that, and remember, ah correlation does not equal causation, but if you do extrapolate that data into people in the longevity space using type
00:30:09
Speaker
tiny, tiny amount of growth hormone as the, you know, from an anti-aging perspective, it's unlikely that you're ever going to see anything. Now, obviously I've talked to some of the world's leading oncologists and people that actually, there's actually people now that work in, i forget the name of it specifically, but this woman reached out to me about peptides and oncology and and and and looking at radiation and looking at cancer specialists. And they've told me that like for the amount of dosing that people take from anything, whether it's a GH agonist peptide, which I'll get to in a second, or growth hormone, there's so little risk of actually improving you know a cancerous tumor or ah expressing a cancerous tumor, even if it's laying latent slash dormant in a body. So I think I like to tell people, because I know I've heard Andrew Huberman talk about
00:30:55
Speaker
well, you know, there's potential cancer when you're taking GL, not GLPs, but TB and TB. Yeah. Yeah. But the truth is it's so little. And like I said, I've spoken to some of the leading experts in the world about this and they've told me that like, it's, it's less than 0.001% if a person is just using a normal dosage. Now that doesn't mean that it can't happen if somebody overdoses. And obviously, as we know, we live in a society where a lot of people think that more is better. Yeah. If a little bit's good, more must be better. Yeah. never works and that's why like literally in 20 years of me being in this space i always say to everybody in every category start low go slow assess your unique individual tolerance your biochemical individuality i love that you said that because that is so true but the primary growth hormone agonist peptides outside of human growth hormone you were looking at like you said you said sermorellin tessimorellin ipamorellin cjc1295 love all of them
00:31:49
Speaker
and i love all of them The least that I like is CJC because I'm one of those people that when I inject CJC, I get a flushing. Sometimes I get a mild nausea. It's a very powerful growth hormone, the increasing peptide or IGF-1 increasing peptide. And that's what that is doing. And I'm one of those people that notices that feeling. So I don't use that peptide personally, but I know a lot of women that use it. I also know a lot of women that use a combination of CJC and Ipa together because obviously they do really great things together. But for sure, for most men,
00:32:21
Speaker
as they get older, they put fat in the belly, right? Center adiposity. And so Tessa Morelin, which is obviously an FDA approved drug known as a grifta, tears through visceral fat in the center adiposity. So if you're going to use Tessa to get rid of belly fat as you age as a man, i don't know anything better. In fact, Tessa is actually better than growth hormone in you know getting rid of fat in the middle, in the middle midsection. Now I'm Personally, as almost guy, I'll be on February 24th, I'll be 55.
00:32:51
Speaker
I and my wife use a super, super low dose of growth hormone in a pen, genotropin from Pfizer, which you know I call it the nectar of the gods. But truthfully, if you can't get that, and it's pretty widely accessible, you know there's tons of offshore pharmacies that will sell it to you. And by the way, it's not illegal. You can absolutely get it and import it into the United States. You can also go to Mexico and get it.
00:33:14
Speaker
If you can't afford it or find it, Tessa as a man is the next best thing. An IPA for a woman, in my opinion, is the best thing. and The reason IPA is the best for women is because, as you probably know, it does not increase cortisol, prolactin, and it also does not disturb...
00:33:31
Speaker
the but body's normal pituitary function. So as we're getting older, you could actually inject ipamorelin two, even three times a day in a microdose and never disturb the body's endogenous pituitary function and natural release of growth hormone and IGF. So I love those products. I think it just really comes down to who you are. There are some women who like a higher, stronger dose of growth hormone agonists. And so they like tessamorelin, but most women that I know who use tessamorelin get water retention. And that's just, again, because it's a very powerful GH bolus or GH burst. And so I think IPA is kind of the best balance. But those are the four primary ones. There's other ones, you know, there's five AOD.
00:34:12
Speaker
There's a couple other ones that, you know, you talked about sermorelin. Sermorelin is an interesting peptide. it doesn't show up In the clinical literature, it shows up as strong as ipamorelin, but if you ask 100 people who've used both, 99 out of 100 will say, oh, I like ipamorelin. I feel the effects of ipamorelin more than sermorelin, but that's just one of those weird peptides that shows so much more in the clinical literature, but then when you use it personally, you don't notice the same, but it does look to be very similar to ipa, just when most people use it, and in my experience, and talking to people that use it, they all say, oh, no, I like ipa more than I like sermorelin.
00:34:47
Speaker
Okay. Now, what about kind of more longevity focus? So maybe mitochondrial with MOTC, epithelium, like what what are you seeing in that area?
Mitochondrial Peptides and Small Molecules for Health
00:34:59
Speaker
So right now, mitochondrial peptides are is is a massive expanding place because you have you know your primary mitochondrial optimizing or expanding peptides like an SS31, which by the way, now is called Lama pre-tide. You can't say SS31 anymore because they patented, they changed it changed some aspect of the molecular formula. And they patent it. So they like sent cease and desist letters to everybody in the research space that was selling SS 31 in December and said, Hey, you can't do this anymore. So now sadly, Biolongevity Labs, we're waiting on our attorneys to give us the go ahead, but we stopped selling it and they did change the name. So they will come after you if you sell it or you mentioned it as SS 31. I had to actually go on jcampbell.com and change all the articles about SS 31 to a lab of pre-type dude. I had to do it in this book too. It's insane.
00:35:46
Speaker
But SS31 slash LamaPretide is a very powerful mitochondrial optimizing peptide. I call it the amplifier peptide. It just makes everything else better, right? So if you're using therapeutic testosterone, if you're living insulin controlled, if you're using a GLP, um it just makes it better. And in fact, if you use it correctly,
00:36:07
Speaker
I feel like you can lower the dosages of the other things because again, it's just amplifying cellular cascades and signaling cascades. And so it's a very, very powerful peptide in that. And then you mentioned MOTC.
00:36:18
Speaker
I think MOTC is the number one peptide for insulin insensitive and metabolically dysregulated people. In fact, in heavy, obese, highly inflamed people, if you give them a strong bolus of MOTC, and that can be anywhere from like two or three milligrams even up to like six milligrams, they all of a sudden have energy, right? And the reason that is, is because when you're fat and insulin resistant, you don't, your mitochondria don't work.
00:36:43
Speaker
I mean, they work, but they're just inefficient. So if you give them a big bolus of MOTC for two or three days in a row, all of a sudden they have energy, they want to exercise, they have more life force energy.
00:36:54
Speaker
So it's a really big needle mover. And then the other ones to mention for sure are five amino, one MQ, Now, 5-amino-1MQ used to be known you know as an oral you know molecule to take, and you could take it at like 100 to 150 milligrams a day, man or woman, and get a good response. But now, most of the research companies and the compounders are selling it as injectable formulation, and it's really strong as an injectable, so you can use a lot lower dose. And then of course we, you know, I don't want to mention, I don't forget NAD plus, right? So obviously n NAD is given in IVs, it's given in patches. It's also given in powders, you know, to orally take, although I think that's a very, very poor, poorly absorbed format of taking any of the powders. I know Dr. Xi is a good friend of mine. He sells a formulation out there and people that use that, you know, will show higher levels of inter-individual NAD in their body from a cellular pool standpoint. But I personally think,
00:37:46
Speaker
that NAD is best injected. Now, here's the thing about NAD+, and I didn't take me, I didn't understand this until three or four years, the more metabolically efficient you already are. So the higher muscle density, lower body fat, the less you're going to feel taking NAD+, versus a less metabolically efficient person who takes NAD, they get that supercharged, like, oh my God, I feel so good on NAD, right? So- Different from 90 to 93 is very different from 30 to 50, right? Like, yeah.
00:38:19
Speaker
But literally a hundred percent. So I, I don't, I used to say, oh, you know, I'm not that big of a fan of NAD plus cause I never felt it, but it really is one of those things where it will still help you. It's just, you're going to feel it more if you're more metabolically dysregulated. And honestly, dude, that's most people.
00:38:36
Speaker
80% of society is metabolically dysregulated now. So they're going to feel that more. But those are the four primary ones. And then i would I would be remiss if I didn't mention like the oral small molecule products, which are amazing. right You've got SLU PP-332, which is called Sloop, or is affectionately known as Sloop. And that's another very, very powerful product. patented research molecule that people are using like the university of florida has done some incredible studies from like 2023 to 2025 where it dude it just literally massively upregulates atp so when you're taking this as an oral supplement you just have energy you have more force production it's amazing i mean every person that i know that uses that men or women all rave about it we sell that product we call it shred max and it's in 100 milligram dosage form and then the other ones which are really becoming big now too, is OS01 or ATX318. And that's also a very powerful mitochondrial optimizing small molecule. So neither are peptides, but obviously peptide suppliers are selling them. And I really see, you know, I was talking to Ryan Smith the other day. I know, you know, Ryan and, you know, he was telling me that he's like, bro, we're on the infancy of these two. He's like,
00:39:45
Speaker
there's probably like seven to 10 more of these compounds that are like in the pipeline that are coming. And so all of these things, all they do is they target ATP functionality in the body and they will improve, you know, ATP production. So the more ATP you have, the more cellular energy you have, again, the more force production and obviously the more cellular energy, the more you're going to burn body fat at rest or burn calories at rest. So they're all really, really good. i think the key as we get older is figuring out what mitochondrial peptides to run while we're using a mitochondrial optimizing small molecule. And I think right now it's kind of anecdotal and people are just deciding based on like, oh, I did this peptide and this peptide. And I also took this small molecule. But within the next year to two years, I think that people will figure out if I'm using this oral ATP, you know, increaser, I should use this injectable peptide at the same time because I really want to control my mitochondria. You know, you hear people talking about so the spin,
00:40:43
Speaker
you know, and over revving your mitochondria if you're using too many things. And, you know, I'm sure that that really is an issue in people, but I think we really are still learning right now, but all of those products are truly
Longevity Peptides and Usage Strategies
00:40:54
Speaker
amazing. And just because you asked about longevity, the other two to mention,
00:40:58
Speaker
or epitilon, right? And then also thymolin. And a lot of people recommend using both of those together. Epitilon obviously improves telomerase production as we get older. It's a Russian bioregulator. It can be injected. It can also be used orally. And then thymolin is also a injectable bioregulator and it helps production of the thymus gland. And I think most people, by the time they're at 50, if they're not really, really taking care of themselves, the thymus gland is almost completely dysfunctional.
00:41:29
Speaker
right by 60 it's barely putting out anything so if you use thymolin and epitolon together you know in these like 10 day stack cycles a couple times a year you'll definitely improve telomerase production and you'll also you know kind of i wouldn't say um you know reboot it but you'll help the thymus gland continue to put out the immunomodulation and all the good things that it does so you'll keep your immune your immune system healthier and more optimized as you age Okay. Yeah. I mean, this is a beautiful segue then, because I'd love to touch on stacks, blends, and cycling and and kind of maybe in that order. So, well, maybe let's talk blends. Blends versus...
00:42:11
Speaker
doing them separate, like the doing the Wolverine stack versus taking some TB 500 and BBC or a glow stack versus doing GHKCU plus TB 500 plus, is it just a convenience? Are there cost benefits or risks associated with doing blends versus individualized? There's no risks. um I know there's a lot of nonsense and there's a lot of influencers and doctors out there talking about how glow and glow destabilize each other or that the products together in a vial ah reconstituted over time can render one of the other ones inert.
00:42:46
Speaker
There may be some science and logical like you know information behind that, thinking that it's true. But all I can tell you is an application, which is going on eight years of those products combined. I've never seen any kind of loss of efficacy or destabilization of the molecule. So I would say that in isolation, they're great.
00:43:07
Speaker
but in combination or in a blend with other ones that actually enhance or synergistically improve, ah you know, the efficacy of them as a blend versus in isolation, I would still go with the blends, but it also just depends on what you're trying to do, right? Like if you're somebody who has a serious injury, a soft tissue trauma, critical issue, I think a blend over two to four weeks is going to be a lot stronger because you're addressing a bunch of different things in the healing you know pathways.
00:43:33
Speaker
um But I don't, you know, I've heard all these stories, you know, our chief science officer, Brian Moscow, AKA the gorilla chemist, he did a bunch of scientific breakdowns on social media about, you know, whether or not Clo and Glo destabilize each other, whether GHKCU is rendered inert by BBC or TV 500. And all the biochemical details and analysis came out of it was like, If it does, it's so minuscule that it's not an issue. And so don't listen to people that say, hey, you're buying bogus peptides from so-and-so if they're a blend because of this or that. So, and again, I just go by my personal use of these products and I've never, ever seen an issue, you know, and I've used the Wolverine, you know, TB500 BPC. Dude, I've been using that since 2009, right? I've kept them in big vials in my refrigerator and used them over a year period. and and I think I should say this because people ask this. like How long will a reconstituted peptide stay you know in refrigeration viable or efficacious? and
00:44:33
Speaker
The smartest biochemists in the world that I know of, and I know many of them, will say you might lose 18% 20%
00:44:41
Speaker
you know efficacy in that vial over a three-month period. But does that mean that it's ineffective? as long Again, as long as you've kept it refrigerated outside of light, you know incandescent, radiant light exposure.
00:44:54
Speaker
No. It's just that you know if it's three months old or four months old, you've probably got to use a little bit more than when you first reconstituted it. So, Is there a point where if it's sitting in the refrigerator for five years, is it probably inert? Most likely, yes.
00:45:07
Speaker
Right. Depending on what it's been exposed to, temperature changes, et cetera. You know, you also got to factor in like, you know, air and oxygen and carbon dioxide exposure as you're pulling it in and out of the vial and stuff like that. But for the most part, it's, it's pretty easy to use a peptide for up to a year. And I would even say a year and a half in a vial that's been refrigerated. Right. I'm not saying it's a best practice, but But I'm saying like if you made a giant jug, right, of BPC and TB500, I call it the Wolverine blend, and you kept it in your fridge and you only used it when you got injured, you probably got a good 12, 15 to 18 months before it loses any kind of effectiveness.
00:45:44
Speaker
All right. And then you just were talking about use it when you get injured. So we've talked about a lot and you'll see influencers that are like, oh, the Hollywood stack and it's eight to 10 things. And like, how do you think about stacks or is it addressing individual things and different kinds of cycling? Can we talk about that?
00:46:03
Speaker
So this is how I always say it Bleeding neck syndrome, right? Like don't have the shiny object syndrome. Address the biggest issue that you have. Does that mean, so let's say you you injured yourself, right? So you're going to use a blend. Let's say you're using the Regeno blend, Cardilax, BBC, TB500.
00:46:19
Speaker
Okay. At the same time, you know, you're like, Hey, I want to use a nootropic. We didn't even talk about nootropic peptides, but I want to use a nootropic. Is that okay? Of course that's okay. When it's not okay is when you start doing everything, right? Like I'm healing.
00:46:34
Speaker
Now I'm doing a nootropic. Now I'm going to take a GH agonist peptide, which, by the way, is usually okay in combination with healing, right? Because they also help with healing. They are increasing natural growth hormone. that you know Those signaling pathways are going to be strengthened as long as you're doing everything else right. You're eating, you're getting enough carbohydrates, again, you know getting enough protein, again, to help protein. tissue repair and rebuilding, et cetera, collagen resynthesis and all that stuff. But I just don't like people who are taking, again, 10 different peptides for 10 different things. Because let's say that I would tell you that it's not that bad, but how are you going to know what's doing what personally anyway? You're not, you don't have a way to track it. So maybe two, maybe three different pathways that you can address while you're using peptides. But for me, it's always, what is the primary issue?
00:47:25
Speaker
Let's address that primary issue. You know, people will say to me, yeah, but dude, I got, I'm, um I'm fat, but I sprained my ankle, right? It's okay. Fine. So use that, you know, Wolverine stack or use that Regeno blend and inject it right into the area along with your geo, your GOP. And maybe you're a mitochondrial optimizing peptide or your GH agonist peptide, but don't get into a thing where you're taking literally 12 to 15 peptides a day for 10 to 12 different things. That's silly.
00:47:48
Speaker
yeah I mentioned before we started recording, a friend had sent me, you had done a sheet talking about dosing and the cycling and frequency. Is that something listeners could access? do you have on your site a way that they can get that kind of information?
00:48:04
Speaker
Yeah, 100%. If they go to jacampbell.com forward slash peptide cheat sheet, they can get that downloadable ah document. And then also on the homepage of jacampbell.com, you can actually get the small molecule stacking guide and also the bioregulator stacking guide. They're all three together. So all you have to do is just go to jacampbell.com and it's on the homepage.
00:48:24
Speaker
Like you said, I mean, we didn't even get into the nootropics. There's so many more places we could go. did threaten you with getting into the regulatory landscape before we jumped Just call me back and we'll talk again.
00:48:37
Speaker
let's Maybe we'll give that a little time to shake out so we we know a little more yeah there. But is there anything before we say goodbye that you want to share with our listeners?
Educational Resources and Podcast Conclusion
00:48:47
Speaker
yeah Oh, the course. You have you have a course um for the education side coming up, right? Yeah.
00:48:52
Speaker
Yeah. So, um, so first off, Andrew, thank you so much for having me on today. This was an awesome talk. We hit a lot of really hot button stuff. You asked great questions and I appreciate it I'd love to come back and we can go deeper on regulatory. It is a very interesting year in 2026. I think, I think that we're going to see profound and lasting change over the next six months. I mean, obviously we're filming this in early February. It's probably going to come out in the next month or so, but, um,
00:49:16
Speaker
there's going to be a lot of change. And I think a lot of the change is probably going to be difficult for certain members of our, you know, call it healing, you know holistic and functional medicine society. But, um, I think ultimately in the big picture, the genie is out of the bottle and they can't put the genie back in the bottle, no matter what they try to do. So it it will only get better. But for people that'll, found this information valuable, they can go to jcampbell.com forward slash free dash info. And you can download a free PDF copy of all the books that I've written, which as of right now are eight.
00:49:47
Speaker
As you, as you and I discussed earlier, metabolic awakening with GLP peptides will be on Amazon and then wherever else you can find books and every version of the book format. Uh, there'll actually even be a video version of the book By February 24th, somewhere between February 24th and February 28th. And then I would just also say that um my a company that I'm built or it's actually already built, it's basically Fully Optimized Inc. is launching a certified coaching program
00:50:17
Speaker
program or protocol or even platform and it's called mind body optimization specialist and this will be the deepest without question at least for now uh information on peptides bioregulators small molecules uh even consciousness spirituality you know basically how do we become an optimized mind body functioning human uh and it's built for doctors, functional medicine providers, holistic health coaches, personal trainers, life coaches, pretty much anybody who wants to have bleeding edge knowledge on how to use peptides, bioregulators, small molecules, and then really put them into a full, uh, you know, practice of where like, Hey, I've done all this physical optimization and now I really want to understand consciousness and the importance of raising our consciousness. So that is coming, I want to say, probably by middle, somewhere between March 15th and March 20th. And that will be, you know, highly advertised and put out there. There'll be probably a ton of influencers that promoting it too. But I'm really, really proud of it. As I told you, I filmed...
00:51:17
Speaker
For 13 days, close to 10 hours a day, there's 15 modules in it and it's very, very deep. And if you don't pass the tests after you finish a module, you can't go on.
00:51:28
Speaker
Right. So it's one of those things where it's like we won't let you progress unless you actually learn the material. So I'm really confident that it's going to really help our community. that's That's amazing. And I mean, it's one of those train the trainers, right? So will help your community. It's going to help more people bring into the community and what's possible.
00:51:46
Speaker
Jay, I mean, you just said, you go down the eight books you've read and rate, like people think peptides this cool new thing. You almost a quarter century into doing this, right? it's ah It's incredible. all you've done leading the way, continuing to lead the way. I cannot wait to have you back because I know, like you said, the next six to 12 months, there's going be a lot more. It's to be really exciting.
00:52:08
Speaker
Andrew, thank you so much for having me today. It was awesome, dude. Thanks, Jay. Thank you for joining us on today's episode of the Home of Healthspan podcast. And remember, you can always find the products, practices, and routines mentioned by today's guests, as well as many other healthspan role models on alively.com.
00:52:24
Speaker
Enjoy a lively day.