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What Kinds of Metabolic Imbalances Can We Catch?
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Watch the video here: https://www.livelongerformula.com/content/what-kinds-of-metabolic-imbalances-can-we-catch
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Transcript
00:00:01
Speaker
Hey there, Christian Yordanoff here. In this video, I'm going to go over a couple of clients' lab tests and just show you what kind of imbalances we can actually catch with a very simple urine collection test that is shipped to your home, collected conveniently at home. Basically, you just pee in the morning and you freeze that urine and UPS or the courier just comes and picks it up. And really, we get...
00:00:28
Speaker
tons and tons of data that I can then use to uncover imbalances in the metabolism and then give you strategies to ah obviously address those imbalances so they don't turn into very, very serious things down the line. So I'll go over examples lab tests of the same urine test from different clients and just to give you an idea of like what kind of stuff can we catch and how does the test
00:01:00
Speaker
um show up in terms of what shows up on a test when someone has kind of decent health and when someone is like in a real poor state of health, right? Which is obviously where we don't, we never want to get to that point. But just it's a very interesting exercise to contrast the two tests.
00:01:20
Speaker
um And then the other thing that's also very interesting is that even though this test on paper, when when we look at the auto-generated lab report side of it, it doesn't look too alarming.
00:01:36
Speaker
There's always, if with a more nuanced... ah approach, there's always things we can still optimize. So think about it, you know, you might, let's say you start, i don't know, sprinting and then it takes you, you know, 20 seconds to sprint 100 meters.
00:01:53
Speaker
ah In maybe in three months, you can get that down to 15 seconds, something like that, right? And then the better you get, the... the more sort of effort and work you have to put in to shave off a second and then you know milliseconds and so on and so forth. So with with this kind of stuff, although we can do a lot ah to improve a person's health with the very basic stuff we do, there's always layers and deeper layers and deeper layers we can go on to continue improving. And although we're not really at that point, we're not really...
00:02:26
Speaker
getting like huge, like 20, 30% improvements in overall health or whatever energy, whatever the case may be. Those 1, 2, 3, 4, 5% improvements, they kind of, we're we're looking at the person as ah as a, like this is the person most important thing for us to fine tune and optimize our health, you know, be that our brain health, our gastrointestinal health, our psychological health. Like this, this is the great, the one great work in life that we have to work on. So for me, it's not like
00:02:58
Speaker
It's not a matter of, oh, we're just kind of nitpicking and just being pedantic and finding, like, micro things to to obsess about. It's more like, no, this is this is not a a crappy Golf 2.0 or whatever from 1989 or whatever. This is a, you know, Ferrari Lamborghini supercar that is expensive, priceless, and, you know, we want to keep it as well-tuned and maintained. And I'm talking about about our body, our health, you know.
00:03:26
Speaker
We want to keep it maintained, fine-tuned for as long as possible, right? So this first test here, these are like the auto-generated lab things. So you can see here, you get these functional imbalance scores of...
00:03:42
Speaker
By the way, if you're listening to this on the podcast, there will be a link in the description to the video on the website where where you can actually watch the video of the lab tests as I go over them, in case you're wondering what the hell is this guy talking about. ah So on the first page of this test,
00:04:01
Speaker
They give you these functional imbalance scores and here it looks really good. Everything everything is like green. Zero, zero, zero. So zero for oxidative stress, which you know need for antioxidant support is the is this sort of bucket of markers, which has some amino acids, lipid peroxides, DNA damage, some nutrients, stuff like that. Then there's need for mitochondrial support. this So this is a mitochondrial dysfunction bucket of markers. And here has a zero here, this client.
00:04:34
Speaker
Then the need for reduced exposure. So toxic toxic exposure is also a zero. So a bunch of like lead, mercury, everything is like green, cadmium, arsenic, detox capacity, glutathione looks good. And need for methylation support.
00:04:51
Speaker
is a four but still green. So if you look at this, like, and I guarantee, listen, I guarantee you, if a doctor looks at this test, they might just be like, ah, this is totally fine. Get out em get out of here. Get out of my office. Go and live your life.
00:05:04
Speaker
You're healthy as a clam, you know? Uh, and this is, this is why, ah This tool would be useless in most doctors' hands. And actually, this is why insurance doesn't cover it.
00:05:17
Speaker
And most, not not I won't say most, but many doctors have not even heard of this test. And I have doctors' clients who have not heard of this test, right? um But a lot of doctors, because they're so allopathically trained, they have...
00:05:30
Speaker
no sort of understanding of the deeper nuances that we can glean here because they're looking to identify, diagnose, treat symptom. right That's literally every all of it. If not, let's just cut start cutting things out of people.
00:05:47
Speaker
So it looks, ah upon first glance, looks good, but I never trust this. And then they give you some further, they give you like, ah so they do give recommendations. So here you can see the green, no recommendation for those vitamins and minerals. Yellow, some recommendation. They actually give you lab-generated amounts that, you know, I don't use this part, but you know you see antioxidants.
00:06:09
Speaker
B vitamins, so they actually do recommend, despite it all being green up here, they do recommend some B vitamins, some minerals, some digestive support enzymes, ah some amino acids and stuff. But again, i and they give you it's kind of cool, they give you ah ah um a little bit of like an overview of what does this nutrient do, and it's kind of cool, so clients enjoy reading this part of the of the report, at least the ones that are more into their health and stuff.
00:06:37
Speaker
um But I don't really use this stuff too much because you know these lab-generated things, you it's like using AI to help with your health. it's What's the point? like We have humans that can do this. Why why are we using AI which which is so inferior still or you know algorithms? And then they give you they show you this really cool...
00:06:57
Speaker
ah basically where oxidative stress and mitochondrial dysfunction ah clues lie. So we have the ah the whole sort of very high level how you know we produce energy. So you have fatty acids go through beta oxidation,
00:07:14
Speaker
a substrate there called acetyl-CoA can be created which can get go into the citric acid cycle and there's a lot of steps there in the citric acid cycle that require of course nutrients to to function and then certain toxic metals can inhibit some of those some of those steps. So for example,
00:07:32
Speaker
Let's say, for example, this step here, citric acid, has cofactors required. But then, for example, arsenic or mercury, they can inhibit this step. So if this is elevated on a client's test, one of those toxic metals, you could then you know think, okay, maybe there's some kind of energy production blockage. So this this gets a little bit more advanced, but it's it's really cool to to start understanding this at a deeper level because it then allows us to ah ah create better supplement protocols for clients that truly are addressing imbalances that we can corrob like we can corroborate with with lab work. But let's not get too kind of in-depth here. So the first
00:08:16
Speaker
page of of markers that we get, you have a bunch of organic acids here. So we have malabsorption and dysbiosis markers. And here, you know, there's one marker kind of trending towards the yellow.
00:08:30
Speaker
ah One dysbiosis marker kind of in the red, but the rest doesn't really scream any like big issues. Now, this client does have some digestion, did have historically some digestive issues, but they were often...
00:08:48
Speaker
just would be alleviated by eating cleaner. So like probably nothing too crazy for us to kind of suspect. The candida marker here, arabinatol, is kind of in the green. So not suspecting like yeast overgrowth or malabsorption or something like, um ah you know, potentially pancreatic dysfunction or insufficiency. Then we have cellular energy and mitochondrial markers. Most of these, again, are kind of,
00:09:17
Speaker
in range, some of them are a little bit on the low end. Now, there is an overnight fast. Obviously, you're you're taking this test in the morning, so you will be, obviously, fasting overnight. So some of these markers can be low just for that reason. So nothing like it's super, like, crazy in the red. Nothing really is really necessarily screaming at me. There's mitochondrial dysfunction or cellular energy production issues. But, of course, we can always, like, there's layers to this. Then there's Some ah vitamin markers, most of them are kind of in the range. Some are trending toward the yellow. So some of these, for example, the biotin markers, because there's two biotin markers, and one is just just in the green but very close close to the yellow, and then the other one is but just between on the border of green and yellow. That to me is indicating...
00:10:10
Speaker
Maybe there isn't like ah a frank biotin deficiency that will cause like symptoms that are textbook symptoms of a deficiency of a vitamin, but it is certainly prudent to supplement this nutrient for a while, right?
00:10:24
Speaker
ah Then other B vitamins, you know, we we use plenty of B vitamins with clients. So this just, some of these markers, I feel like we could bump up some of the B vitamins,
00:10:39
Speaker
but probably because normally we take these we do these lab tests before we ramp up the full supplement protocol, I think it's it's not probably a lot of these markers are probably going to be in a much better range after the the full supplement protocol has been started by the client. So a lot of things.
00:11:00
Speaker
The licensing by the time we see the markers, could be like three, four weeks after the client's in the program. um By that time, a lot of things that are kind of out of whack or likely already have been addressed by the by the protocols that we create for the clients. or are on their way to being addressed. So nothing too worrying here either. Then we have these neurotransmitter markers. So these are proxy markers. And there's a really cool one here called quinolinic acid, which is actually a marker of neuroinflammation. So think neuroinflammation, think very, very early stages of some kind of dementia, Alzheimer's. That's kind of that's like of at a very basic level.
00:11:46
Speaker
if there's a lot of neuroinflammation for a very long time, we're we're talking about neurodegeneration. So we if something like this is in the yellow, already we want to just nip it in the bud really quickly.
00:11:56
Speaker
in this In this case, it it looks like it's at ah at a healthy range, so nothing to worry about. Some of these markers here can indicate vitamin B6 deficiency if they're out of whack, but not nothing is really screaming at us B6 deficiency so far. Then we have catecholamine marker, so like your dopamine, your adrenaline, stuff like that. And this is something I'm kind of seeing within in a fair portion of people is like a low dopamine. And then there's the serotonin marker, 5-hydroxyindoacetic acid, 5-HIA is the marker that's kind of trending toward the yellow.
00:12:36
Speaker
And this this I actually suspected before we we got the lab test because like I can kind of based on people's symptoms. and With this client, it was like you sleep issues and low energy type stuff. So based on the presentation of the client and my clinical assessment, I can kind of preempt. and i'm almost like Sometimes um I even tell clients during our you know initial clinical assessment,
00:13:02
Speaker
I tell them, I'm pretty sure when we get the lab test results that you know your dopamine will be high and potentially your serotonin breakdown marker might be you know elevated or close to the yellow at least. And in this case, it was the case.
00:13:17
Speaker
like Luckily, in this case, we actually had already started doing stuff around boosting dopamine, breaking down serotonin and stuff like that. So again... At this point, it's just corroborating my hypotheses earlier on. We're not really changing much at this point. We're just kind of holding steady and just adding some some things on top, just kind of further optimizing. right Because you know you you you do this a few times. you see You start seeing patterns and then you start preempting things. That's why I always tell clients that are like...
00:13:48
Speaker
oh but i don't know if i can afford these lab tests first of all the lab tests are super affordable uh but i always tell clients i don't want ever the lab test to be the deal breaker of whether we get to help you or not because Whether or not we do a lab test, i've I've had plenty of clients that they do a bunch of lab testing. They come to me. They upload the the lab tests in the client portal.
00:14:14
Speaker
I look over the lab tests and then I ask them, okay, what was done about this marker? What about what was done about this lab test? The stool test. And so many times I hear, well, that other practitioner did nothing about this.
00:14:25
Speaker
Or they ran ran the test themselves and they did nothing about it. So the... the The key isn't running lab tests and and getting pieces of paper with numbers on them.
00:14:36
Speaker
The key is doing the protocols that help the person get healthier. right Now, the lab tests can be very helpful. Of course, like I said like i say it often, they help us catch imbalances that the naked eye cannot catch, which is super valuable, invaluable.
00:14:56
Speaker
um But a lot of the times, because i've seen these patterns over and over again, we already give clients, you know, some aspect of their protocol is already designed two ah address these issues. So whether or not we get the lab work showing that issue is there, we're still going to do something about the issue.
00:15:20
Speaker
right So I never want folks to ever think that if I can't do the lab test, I can't do the program because ive i we we've done a lot of great work with a lot of clients without doing any lab tests either. it just I often say if if you can afford it,
00:15:38
Speaker
Like it's not going to like you're not going be in debt that you still buy groceries that month and all that stuff, you know, or you have some savings. If you can afford it, I would do it because I can't think of a better way to, you know, invest our money than in our own health. And, you know, you talk to people that might have like a...
00:15:57
Speaker
401k stock portfolio crypto portfolio that's like six figures plus and they're putting away money and they might have like airbnbs and then they then when it comes to like a few hundred bucks for a lab test they're like i don't know like no that it should be like the complete opposite like we need to be investing in our health first Then we create our budget. you know that kind of that's kind of It's like that the funny bro science video.
00:16:24
Speaker
It's like they asked him a question. What if I can't afford to buy protein? Or what if protein my budget doesn't allow to buy protein?
00:16:36
Speaker
You got it backwards, man. You buy your protein and then you make your budget. So that's kind of like i'd like I buy my supplements, buy the best quality food I can afford.
00:16:47
Speaker
And then I make my budget after that, you know? So that's kind of, that that's the switch we have to make. Because listen, in 10 years' time, all the things that you thought were more important than this kind of stuff, you'll see they were not more important. And in 20 years' time, even more so.
00:17:03
Speaker
So the sooner we make that switch that, okay, a little bit lab testing, a few more supplements here and there, better quality food, ah these are These are the most important supplement investments we can make to today.
00:17:17
Speaker
Not you know buying Amazon stock or whatever the hell. ah Then the toxin and detox markers for this client. He was like about six weeks into the program, so he was already doing some stuff. I think we took the lab test a little bit into he was already doing some stuff.
00:17:37
Speaker
But he was already like... you know doing things on his own, right? So his pyroglutamic, which is like your glutathione marker, that's like almost smack bang in the middle, which is really good that you don't want it to be in the yellow, definitely not in the red either direction because that indicates your detox capacities are overburdened or there's some kind of deficiency but possibly from the diet or nutritionally that is not allowing you to, you know, to detox as well as you could.
00:18:06
Speaker
Then there's a couple of uh toxin markers actually styrene and mtb it's like a gasoline additive these are in the green this is good because you i often see these in the kind the yellow and that just indicates people are very likely just being exposed to like gasoline fumes from driving a lot in traffic so i like to see this that's you know it's always good because um you know the the less The less toxic exposures a person is dealing with, the easier our job is to help them optimize their health. So looking looking okay so far.
00:18:44
Speaker
Then we have oxalate markers. There was one there was one marker here. ah elevated into into the red but there is actually a very ah a very valid reason why that's elevated.
00:18:59
Speaker
Most likely it's because of um increased hydroxyproline consumption, the the amino acid, due to some of the dietary changes we did with the client. so That's probably ah the reason most likely, so nothing to worry about there.
00:19:15
Speaker
Then the lipid peroxidation slash oxidative stress marker. So we have the DNA damage marker here, 8-OHTG, which just really rolls off the tongue. 8-hydroxy-2-deoxyguanazine. Say that out loud five times. you know ah A 2, very low. ah you know Really one of the lowest I've seen. So DNA damage marker looking really well, looking really kind of you know in ah in a very healthy range.
00:19:42
Speaker
And then the lipid peroxidation, so this is 5.2, kind of, you know, pretty far from in the yellow territory. Could it be a little bit lower? Sure. There's definitely stuff in the protocol that will help to, um you know, over time probably lower this. I would say, would probably bet good money that if we were to do this test, let's say in three months, this marker would be lower.
00:20:03
Speaker
But it's still not in ah like in a range where I would at all be worried. Because it's not even in the yellow, never mind in the red. And then there's some amino acid markers here. and now these these A lot of these amino acid markers will tend to be like on the low end because, you're again, you're fasting overnight and then you're taking the urine sample in the morning. So it's kind of normal that that they're low. But what I saw here, the biggest thing that screamed out to me here was that the one amino acid here, methionine, was very high. It was actually not only in the red, it was off the chart. So the range is 2 to 16.
00:20:44
Speaker
and the marker here was, ah the value here was 33, like almost, you know, more than 2x over the top of the range. So to me, that could be some kind of methylation issue. and That's probably why they had me the the methylation ah was green up top there, but it was a 4.
00:21:04
Speaker
So this is where some kind of nutrient in the methylation cycle could be ah deficient. And this is where, once you see this, then you can start going back here, up up up top, and then you can start re-evaluating some of these vitamin markers, some of these neurotransmitter markers. You can start evaluating. For example, if that methionine was high and then one of these kinuronine pathway markers was elevated,
00:21:34
Speaker
ah which can can be a sign of a vitamin B6 deficiency, I could then say, okay, that's possible that vitamin B6, because it it can be used to you know ah ah in that that sort of the methylation homocysteine cycle.
00:21:50
Speaker
That could be low, hence why the methionine has built up. And then we start kind of going back and, or could it be folate, B12? And then you start evaluating all of these, and then we can make a decision what nutrients to add to to see if if some kind of blockage in the methylation pathways can be unblocked. And what I actually told this client specifically, I don't normally do this, although it's a good marker to run once in a while, I actually told the client to go and get his homocysteine blood marker checked because if that was if that comes back as
00:22:31
Speaker
somewhat elevated, like 11, 12 plus, that for sure indicates a methylation issue which could be alleviated by certain B vitamins, right? that That's one thing. But then further from that, what I would do at that point is I would be thinking,
00:22:47
Speaker
Could there be some kind of genetic polymorphism, SNP, like a single nucleotide polymorphism or multiple in some of the genes like the MTHFR, MTR, MTRR, all these genes that are part of these methylation sort of enzymes.
00:23:04
Speaker
So at that point, I would probably do, ah they're they're pretty cheap, these nutrigenomic tests, are like 300 bucks. But I would do that test. And and we don't like I don't necessarily tell everyone to do that, although i you know it it doesn't hurt. like i've I've done a few on myself and even on my daughter when she was born. We used a fake name, so we don't even like have to use a real name if people don't want to ah you know have their you know you know a name associated with the data.
00:23:31
Speaker
But um it's it's good to know because... We all have certain genetic vulnerabilities. It's kind of a little bit luck of the draw, but knowing them then allows us to put in a nutritional strategy to that allows us to ameliorate those the risks caused by those um polymorphisms. For example, I have the MTHFR C677T,
00:23:56
Speaker
um c six seven seven t I am homozygous for that one, which, you know, it's bad, quote unquote. And when I got that test back in like 2018, when I got the the the results, i was like, oh my God. That was like, i was at first, i was like almost noceboing myself. Oh my God, this is so bad. Like, ah what was me?
00:24:23
Speaker
And then I just realized, oh, no, you just take a few few nutrients and make sure that you know your homocysteine doesn't creep up, and that's kind of kept in check. And it's super easy to put in a strategy for life, and you know this with one genetic test. You know your vulnerabilities, a little bit of analysis. You know for life what to do to ameliorate some of these issues. and then But what was interesting is as I was digging a bit deeper into that at the time, I saw that a lot of the issues that run in my family,
00:24:53
Speaker
actually have been associated associated with that MTHFR polymorphism. So it started to make a lot of sense. then Then we have a vulnerability in the family and it has been expressing in you know depression, atherosclerosis, blah, blah, blah, you know miscarriage, stuff like that.
00:25:14
Speaker
And I just wonder, my family members, that of course, they wouldn't listen to me at the time, especially that was so long ago as well. They thought this was just another oh that's just another thing. He'll get past this and he'll move on to another thing. He doesn't know what the hell he's talking about.
00:25:29
Speaker
So I'm just wondering, a lot of the the stuff in my family that we've had as ailment, I wonder, could it have been prevented from you know We're just knowing this and putting in this nutritional strategy. So anyway, we with this client, we're going to put in some stuff.
00:25:48
Speaker
We already did put in some stuff around this, and then that homocysteine marker will give give us more clues as to you know should we do a little bit of a you know ah further the investigation with nutrition genomics.
00:26:02
Speaker
testing, but in all cases, no matter no matter what the client chooses, there are some nutritional strategies that are good to do to make sure that that homocysteine is kept in as low as possible within kind of reason, like 7-8 type ah in terms of range.
00:26:21
Speaker
Because it's actually um an independent, quote-unquote, cardiovascular risk factor, you know, apart from, like, cholesterol and all this kind of nonsense, high blood pressure, which is legit. But it is an independent risk factor. So there is, like, this inflammatory component to methionine, you know. So it's important stuff like this that when we get a clue on the test that we we just do a little bit of deeper investigation when prudent because sometimes, again, we we're talking about can we prevent issues from happening, you know,
00:27:01
Speaker
30 years down the line. And there's there's more stuff here as well. Obviously this this is already 27 minutes. i want to move on to the next test. There's other stuff here that we we can kind of discuss. um But I just want to go to the to the to the last page here with the nutrient marker. So you can see with this client the toxic metals, all of them are in the yellow.
00:27:25
Speaker
There's no green range for toxic metals, so it's only yellow and red. But nothing was in the red, right which is great. um Some of them were below detectable level, which is great. Then the nutrient elements, this is where we can see if something is in the yellow to the red. This is this is interesting because this indicates the body is not excreting the nutrient, the mineral, for A couple of possible reasons there. There's very a severe lack of it in the body, like a deficiency, and or a you know lack of it in the diet. And when that happens chronically and the body starts to kind of like, man, I'm running out of this stuff. I need this stuff.
00:28:08
Speaker
ah There's not enough to go around. Then anything you ingest, the body is going to hold on to. It's really smart that way. and ah that means you're not going to be excreting it in the urine. For example, here the manganese, right, below detectable level.
00:28:24
Speaker
The only one that's of concern here when it's below detectable level is the iron because that can actually mean that iron is not being excreted which is actually not good, right, because iron can, as it builds up in the body, it can cause oxidative stress. That one is that is something that there there are there are pathways that can be boosted here. But things like manganese, if it's below the detect detectable level, something like selenium kind of edging between red and yellow, ah you know, chromium is in the yellow. That just indicates that we need to do more with the minerals, which we were already, you know, the client was already, like i said, on the program several weeks. So we're already already already doing some stuff with minerals, but this just indicates we need to do more.
00:29:10
Speaker
So these are the kind of things that this is, remember, this somebody like about 40 years of age or so, decent health, just lack of energy, sleep is not great, some gut stuff over the year, just various like...
00:29:24
Speaker
Nothing like mega debilitating by any means, you know. But there's a lot of stuff that we can still catch. And this is the thing. A lot of guys out there are a little bit like stiff upper lip. I'm fine. I'm fine. Until they're not. And they just kill over. And, you know, gonzo.
00:29:43
Speaker
um So a lot of guys, they can be fine, fine, fine. Until they're, you know, literally, yeah you know what I mean. ah So we, it's important.
00:29:55
Speaker
For us to never judge necessarily that I don't have visible outward symptoms, therefore everything is fine in my body. Because in today's world, it's impossible. I have not done this test on one person where everything was like satisfactory.
00:30:12
Speaker
Even with some very healthy people, like my Major League Baseball pitcher guy, we ran this test on him. you know We found stuff. Charlie Robinson, my buddy, the macroaggressions host, super healthy guy. a he It still amazes me that like how few imbalances we find with him on the lab tests.
00:30:32
Speaker
Like I said before, we got to study this guy like scientifically. But we still find something, if you know what I mean. Now, let's contrast this.
00:30:43
Speaker
with somebody who last year was hospitalized. ah I should say older gentleman than the previous client, maybe 25 years or so older. But he was hospitalized in Asia with some kind of intestinal parasite.
00:31:02
Speaker
he He told me when when actually we when we went over his lab tests earlier this year, ah He told me that once I explained all of the the imbalances I see on the tests, he told me, oh well, that explains why last year i felt like I was dying.
00:31:21
Speaker
Right. Now, keep in mind, this lab work, we got it about, i guess, six to seven months later after that incident with with the hospitalization.
00:31:34
Speaker
But as you can see here, the we have the on the last test, we had an all green, 0, 0, 0, and a 4. Here we have 8, 7, 7, and a 2. So red, yellow, yellow, and then one green. So oxidative stress, neutral antioxidant support, high 8%.
00:31:54
Speaker
Need for mitochondrial support. So this this just indicates mitochondrial dysfunction which of course indicates issues with producing energy and if you can't produce energy, it's like if your car runs out of fuel type thing. or You can't do much with your car, you know, you can probably like nap in it or something, you know, be protected from the elements but not much else useful. Similarly, if you can't produce energy in the body, a lot of things start shutting down because they need energy, they need fuel. ah Need for reduced toxic exposure, A7, right? So we'll discuss that later. And then methylation support, it too. So let's see what the lab... Okay, so look, the lab are recommending severely... so or very strongly ah recommending antioxidant stuff, B vitamins, yellows and reds, and some minerals, GI support, amino acids. So even...
00:32:49
Speaker
Like even the automated report knows man this this this guy needs a lot of support and then when we start looking at the actual markers I'll just scroll down through all of this stuff So when we start looking at the actual markers, this is where it starts to get a little bit Crazy, so you can see some markers here around malabsorption and dysbiosis some markers that are off the charts like four x
00:33:22
Speaker
4.5x of the charge, phenolacidic, that's a malabsorption marker. This biosis marker, 4x above the range, another one above the range here. a couple of, in the yellow, one almost in the yellow. a couple, the candida marker, something like 4x over the top of the range.
00:33:42
Speaker
another And then these are other fungal markers here, citromalic and tartaric. So what this is indicating is digestion issues, like breaking down food and absorbing it, so severe severe disruption probably of the the gut lining, which is you know you secrete enzymes there and supposed to those cells are supposed to absorb then those nutrients. so indicating Malabsorption, putrefaction probably of the food, issues digesting the food, candida overgrowth, right? Because he was given some antibiotics as well, so that could cause further imbalances there. Then energy production, cellular energy and mitochondrial markers.
00:34:25
Speaker
Fatty acid metabolism of the chain. Now, this can indicate these two fatty acid metabolism markers are probably indicating he's oxidizing a lot of fat.
00:34:36
Speaker
And here's what you have to understand. All the keto and low carb and the fasting people that tell you, know you you have to become a fat burning machine. they don't realize people on their deathbed are basically like burning a ton of fat, you know cancer and stuff like that. so Burning a lot of fat is and shows the body is in an extreme stress state. right so There's further here carbohydrate metabolism, this you know yeah stuff in the yellow. so This is indicating issues with carbohydrate metabolism, further ah you know energy metabolism issues here. so Just in general, this screams mitochondrial dysfunction which of course then causes energy production issues. And then if you don't have sufficient energy, you can't deal with toxins, with bacterial stuff, fungal stuff.
00:35:29
Speaker
It just indicates severe severe also malnutrition because also this gentleman was largely vegetarian for a long time for for various reasons. And this is just end stage end stage kind of ah dysfunction culminating. Then the the vitamin markers, nothing too crazy out of the range here, a couple of things out of the range. So definitely B7 could be added here, but nothing like too crazy on the side of things. Then the neurotransmitter metabolites,
00:36:03
Speaker
This quinolinic acid, remember I said that's a marker of neuroinflammation. That's like a 7.9 in the yellow, above the the middle of the yellow range. So that's that's indicating some neuroinflammation, a.k.a.
00:36:20
Speaker
you wrote neurodegeneration. That's because when you have inflammation, that damages the tissue. So whether no matter where that inflammation is, tissues around in the surrounding areas are going to, you know, there's going to be collateral damage. It's like ah sometimes I ah talk about like...
00:36:36
Speaker
imagine like your bookshelf catches on fire and you take the fire extinguisher and then you extinguish the fire but then your books are damaged from whatever you know foam stuff it was in the fire extinguisher so with inflammation although it's a initiated with good intentions by the body when it's chronic caused by a bunch of stuff in the body, um you know whether that's toxins, infections, ah food sensitivities, whatever immune immune system reactivity is going on, that inflammation that's chronic becomes damaging to you know the tissues. Then, and what's interesting here is the serotonin marker was also like what two times above the top of the range off the charts. That's the highest I've ever seen it.
00:37:25
Speaker
And generally when the serotonin breakdown marker is high, people tend to have more health problems. The higher I've seen it, the more health problems people have, so which is indicating further a lot of got further gut dysfunction, right? Because ah ah you may you have heard that 90% of the serotonin in the body is made in the gut.
00:37:47
Speaker
And so if there's a lot of gut dysfunction, like intestinal permeability, leaky gut type stuff, then Some of that serotonin can actually get absorbed systemically. And then we also know that certain amoeba and parasites and stuff like that, they can actually secrete serotonin as well. So it's it's possible that there's something else in there. But this is a ah a marker of very severe stress.
00:38:13
Speaker
And then actually this this serotonin will then feed into the... ah ah the cellular energy side of things because it's it's basically a metabolic sort of inhibitor.
00:38:26
Speaker
So because because it it rises in times of stress, one of its mechanisms is to actually slow down the body, slow slow down the sort of the mitochondrial um respiratory chain, where you know the energy production pipeline. it's kind of That's a sort of a survival mechanism. So if you're under severe stress for whatever reason, fasting or you know starvation or whatever the case may be, it could be psychological stress, ah Any stress to the body, it's ah it's a survival thing, right? So it will slow down the metabolism as a result of the stress in order to to prolong its survival. So that's kind of, i can see how that this high serotonin um can be potentially disrupting some of these, you know, the cellular energy mitochondrial pathways.
00:39:17
Speaker
Then the toxin and detox marker, so here you can see the glutathione marker pyroglutamic is in the yellow. So remember the previous client it was almost smack bang in the middle of the green. Here it's elevated.
00:39:31
Speaker
And if it's elevated or low, in both cases it's indicating some kind of glutathione deficiency. In this case, I i suspected that the the just the client would just the vegetarian sort of...
00:39:48
Speaker
ah ah the sources of protein in the vegetarian sort of fare are really not great, not very bioavailable. I would say probably just like like a chronic protein deficiency here. And then probably a lot of toxic exposure from ah various sources. For example, you can see the styrene the MTBE markers, whereas they were in the green with the previous lab test.
00:40:11
Speaker
Here one is in the yellow and one is in the red. So probably a lot of exposure to like fumes, you know, and understanding the context of the client, I would absolutely just knowing like more about the person. I know that that that is definitely true. So they were definitely getting exposures.
00:40:31
Speaker
Then we have the the oxalate markers, nothing too crazy there. Then the oxidative stress markers, we have the lipid peroxides off the charts.
00:40:43
Speaker
So I had never before this test, I had never seen any of these oxidative stress markers beyond the yellow. Now his 80HDG, the DNA damage marker is in the yellow 11, which very concerning, like the previous one was two on the other client's lab work.
00:41:01
Speaker
So we're talking, you know, more than five-fold increase of DNA damage. Now, this gentleman is older, but you know this is very, very concerning.
00:41:11
Speaker
And then the lipid peroxide, man, that's like so this is this is probably the one of the most concerning things about it because that's just indicating a lot of... a lot of lipids in the body, which could be cellular components, it could be brain cells, it could be mitochondria, it could be cells anywhere in the body that you know they have these lipid things, lipid portions
00:41:37
Speaker
you know in the organelles and stuff like that. So what's what's indicating is that the oxidative stress from toxins, whatever inflammation, whatever whatever the cause is, a lot of that is causing a lot of oxidative stress, which in a very simple term is is just damage. Like imagine you have a wall a structure, a house, and has walls, and then the elements start battering it, you know tornadoes, hurricanes, and inside the house or around the house, you find like bits of brick with cement, like that's what they're measuring in the urine, they're measuring lipid peroxide, so what used to be like a a lipid, like a full brick,
00:42:21
Speaker
a fatty acid or some other kind of derivative from a fatty acid is not like some kind of other thing, like so half a brick or like a chunk of a brick or a bunch of stuff. So that's just in this is quite simply indicating damage two structural components inside that person. So you can imagine cells getting damaged, organelles getting damaged, and that gets excreted in the urine. Now, if you understand from a functional perspective that when a cell gets damaged, it can also hurt cells around it. if it's you know if it
00:42:53
Speaker
If it dies, it could like damage the the the ones around it, for example. But that those cells are part of a tissue which could be like in the lungs, it could be in the brain, the a blood vessel, it could be the heart, ah the skin. So that tissue then is part of an organ.
00:43:11
Speaker
right So the more damage happens to cells and tissues, the more damage happens to the organ. And then sooner or later that organ will accumulate enough damage where it will stop functioning correctly.
00:43:23
Speaker
And that's when we have symptoms. And then when an organ is not functioning correctly, organ systems start to malfunction. That's where you have you know various other health problems start occurring. By this point, the person has the very serious symptoms, right?
00:43:40
Speaker
And this is way, way late in the game. So anytime we're dealing with markers like this, like we're talking someone that's very, weight really late in the game. And I had hate to say it, but a lot of people that get to the stage where the lab works, show stuff like this, a lot of people probably are very close to the point of no return if you know what i mean uh so this particular gentleman was very lucky that our paths crossed um because you know like i don't even i don't even want to think what could have happened you know um then
00:44:19
Speaker
here we have what's interesting is the arginine here was quite high while most of the other stuff was like in the in the range or low i'm kind of now i see it now i'm kind of thinking the arginine because it's a precursor to nitric oxide i wonder is the boy producing more nitric oxide maybe it's like to to deal with the potential infection i think because we we can use nitric oxide to like kill stuff So i wonder, maybe that's why it's elevated. I wonder.
00:44:50
Speaker
um But in the citrulline as well, it's kind of elevated. So just some of these some of these markers now, I'm looking them with fresh eyes.
00:45:01
Speaker
i wonder, could this proline be elevated because of the the state of degeneration where the body is breaking down collagen? Proline is a collagen...
00:45:12
Speaker
is an amin amino acid found in collagen structures. So i wonder, is the body just breaking up collagen for the amino acids so they can be turned to like fatty acids, ketones or ah glucose or just be used for other purposes in the body for more, shall we say more ah vital for survival functions. But yeah, just overall, like I mean, even up to now, like this this screams to me, this this person is in a very end stage of this health health issues and dysfunction. But then when we get to the the toxic metals, things were get even crazier. I've never seen five toxic metals in the red on a test. So we have arsenic just into the red, barium way, way into the red.
00:46:00
Speaker
Cesium, nickel in the red as well, those two in the red. Thallium as well in the red and actually six, tungsten as well in the red. And then we have you know a few others kind of close to...
00:46:16
Speaker
to the border, red and yellow, rubidium, cadmium, aluminum, aluminum, depends on where you're at. And then there was, of course, iron below the detectable level, so another case of like issues with excreting iron, which can further cause oxidative stress in the body.
00:46:33
Speaker
And then chromium, very low, vanadium, so like selenium, molybdenum on the low end. So I then look at this magnesium, Magnesium was super crazy off the charts elevated. It was actually so elevated that it was above the upper limit of the technology to measure it, right? So they have a you know below detectable level for the markers, but they also have like, there's there's a point where it's above the upper limit, so they're just like, with Basically, it's a shitload of magnesium. So what this indicates is another thing. Under stress, the organism will waste, will kind of excrete certain minerals like, for example, zinc, um magnesium, also sodium as well. So this is just likely showing further corroborating that the person is under severe stress here.
00:47:33
Speaker
and then also potentially the calcium being this high. I can't remember if he had started the the calcium and magnesium supplement i I had recommended months earlier, actually. But um if the calcium is high, that I wonder, this is now me speculating at this point, but could it be because of potentially bone getting broken down to provide you know the collagen amino acids?
00:48:01
Speaker
that the body can then use for energy, for other more vital, for survival functions, for detoxification, which is clearly taxed here. so But like this this is just an interesting couple of case studies where we can contrast someone in their 40s, some health challenges, nothing too severe, you know some fatigue, low energy, sleep issues, some gut stuff, things like that.
00:48:26
Speaker
And we can still find a lot of imbalances there. Right? And again, minor imbalances, nothing nothing like insane by any means, but there's still something to optimize. And then on the other hand, someone who was just in it in this sort of state of decline for a very long time, and this is how it can manifest on these lab tests, you know,
00:48:53
Speaker
And obviously you don't have time to go in full depth on all of this stuff. But you can see why some a test like this is so valuable to run because Of course, we never want to end up in this more end-stage scenario for sure, ah but we also don't want to let things fester under the surface without our knowledge of this you know going on for years and decades because a lot of the time, by the time, some let's say the neuroinflammation marker the detox marker, by the time we catch that as you know deficient or elevated or whatever,
00:49:35
Speaker
By the time we catch that, you have to understand that a lot of the body is amazing at like maintaining quote-unquote homeostasis, keeping it together, keeping your breathing, functioning, doing all this stuff.
00:49:47
Speaker
But a lot of trade-offs are made, right? So you you can imagine if you don't have, let's say, household doesn't have ah enough of a budget for everything, like repairs and food and electricity. So over time, they might like...
00:50:02
Speaker
be able to pay the electricity bill and get food but over time as the household you know they might not be able to make repairs so the household will deteriorate over time when the budget is way below what the the full needs of the household are. so similarly in the body the body will continue to function for a very long time. That's why you see like really old folks that like are in really rough shape.
00:50:25
Speaker
They can barely function, but they're still alive because the body is good at maintaining us alive in times of severe stress and lack of nutrition and toxicity and so on. But the idea is let's not ever get there and along the way let's not allow little things like this become big things down the line because again if you're not detoxifying things well today you you might not feel any different but next year you might have a decline one percent that's imperceptible and the year after that that might compound
00:50:59
Speaker
And then it might compound and compound and compound. And in 10 years, you you could be like, oh my God, I'm like 50 or I'm 60 and I can't get out of the bed. And it's because when you're not detoxing, what's happening? It's not just, you're not detoxing. Stuff is building up.
00:51:14
Speaker
Further dysfunction and damage is being caused peripherally, you know? So this is where we can kind of... ah open the floodgates to dysfunction. That's why a lot of folks, they they can just have a very precipitous decline at some point in their life. So we want to get to the point where we we make sure we stay resilient and we catch... It's like, it's like think about it, just to give it an analogy.
00:51:38
Speaker
If your car... um If you take, it like, just, I think last year I took my car. The guy told me there's something on the alternator that is not working right. it will It will be fine for a while. The car will work, but eventually it will it will kill the battery.
00:51:58
Speaker
Then you need a new battery, and then you need to eventually change the alternator and stuff like that. So what most people do is what I did is, like, okay, how much is an alternator? Okay, like, that's... Kind of affordable.
00:52:10
Speaker
ah So i was like, let's just change the alternator, you know, and avoid the issue later on. And then the guy was like, you know, let's try to... Let's see if the battery lasts you another while. It might last. I'm like, bollocks. I'll be back here probably next week. And I was like back there next week. It lasted two days. And then the battery like was dead in the morning. i was like, oh, geez, now i have to deal with this. um so But then you just replace the alternator. You replace the battery. And people are like, oh, it's $200, whatever, $500. Just get it done. I don't want a bigger issue down the line. I want to stranded.
00:52:42
Speaker
on the side of the road, you know, 100 miles from my house. Similarly with the body, we need to take this approach. It might be a marginal deficiency of something. It might be a marginal incapacity to detoxify optimally.
00:52:57
Speaker
but the longer that is left unchecked, the more likely down the line can cause issues that are going to be a lot more ah ah impactful than our car having problems. Because when it's your body, a lot of people that are blessed with good health, you know, bless them, happy for them that they're healthy, but they sometimes don't appreciate...
00:53:20
Speaker
the good health and they're like, I'm gonna be fine forever, like I was in my 20s. And then as soon as you were met with a health problem, you're like, oh, okay, well, health is important. This is the most important thing I need to invest in.
00:53:32
Speaker
ah So this is this is just, of course, one small aspect of the Live Longer formula. not Like I said, not all clients even run this test, but it's it's not necessarily the test that's so important because like after a few years, we might be running a different test. like ah Two years ago, I was running just organic acids tests. like It would be mostly just these markers. And now this one became available...
00:53:57
Speaker
So now we got more markers, so there could be other tests and other markers that could be useful. um So it's it's not really about the test. It's about, I always tell people, it's about ah assessing your health and then you doing the stuff that I recommend and then us supporting you along the way to make sure you do it and you make to make sure you do it right.
00:54:21
Speaker
right And you don't just do the things you think are important or are easy or you know have some kind of you know mental blocks to to doing some of the other stuff. That's the important part, is doing the stuff and getting the support along the way.
00:54:34
Speaker
Because a lot of people, would they they just give up on their own. so This is the kind of stuff we can catch. Super fun. i love I love analyzing these things and kind of putting connecting dots and putting things together. Sometimes I sometimes i feel like I wonder, especially with with a client with less less stuff going on and they feel better and we're just optimizing, sometimes I wonder are they going to perceive that I'm like overzealous and sort of over-nit-peaky with the stuff, but I always say I would rather I would rather kind of err on the side of more ah support and caution and making sure that minor things are get addressed now than not because, I mean, that's why you came to me. That's what you came to me for, right?
00:55:19
Speaker
You came to me for for me to... get my eyes on your you know your diet lifestyle nutrition gut health and give you you're like coming like a i see every client no matter their state of health like a like a prize horse like a prized uh like elite athlete and i'm not just trying to get them to like run the sprint in 20 seconds I'm trying to get them to get to an an elite level for them. It's not a competition by any means, but for them. I want them to be the best they can be because I know most people are like, at best, at best, like 70% of their true potential health-wise, metabolic health-wise. you know And a lot of people make up that deficit by stressing their body, by pushing their body.
00:56:11
Speaker
cortisol, coffee, you know energy drinks, sleeping less than they should and they just on overdrive, you know but that doesn't end well.
00:56:22
Speaker
We should be able to do that without having that kind of push, the artificial push. not saying you shouldn't have the coffee or whatever, but it's it's It shouldn't be necessary to to to function at your peak, if you know mean. Anyway, I hope you found this useful.
00:56:41
Speaker
If you still have not booked a metabolic function assessment with myself or Ryan, our head of client success, make sure you do so so that we can see how we can be of service to you. Okay? Thanks for watching, and I'll see you on the next one.