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AI Meets Bitcoin in Singapore — and Why the U.S. Is Back in the Game with Jesse Darnell

The Charlie Shrem Show
The Charlie Shrem Show

4 plays · Oct 30, 2025

The U.S. crypto scene is finally waking up. After years of regulatory uncertainty and innovation flight, the winds are shifting. Charlie Shrem sits down with Jesse Darnell, [https://www.instagram.com/jemappellejesse?igsh=anA5OHpxdTJnZm1x&utm_source=qr] former Marine and founder of ADVXNCE Protocol, fresh off Token2049 in Singapore, to talk about why global builders are suddenly turning their eyes back to America. They dive into: What Token2049 reveals about the real direction of crypto in Asia How the U.S. is quietly reopening for crypto innovation — from Wyoming to D.C. The rise of “AI + Blockchain” startups and why VCs are finally paying attention again What it means to build a company that’s both community-driven and battle-tested Lessons from the Marines on leadership, pain, and moving fast in chaos Why meme coins and serious protocols actually depend on each other It’s a grounded, hopeful conversation about where the next wave of building will happen — and what it’ll take to win. Jesse Instagram: https://www.instagram.com/jemappellejesse Thank you for listening to The Charlie Shrem Show. For more free content and access to over 400 episodes, visit www.CharlieShrem.com [http://www.CharlieShrem.com]. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com [https://pcm.adswizz.com] for information about our collection and use of personal data for advertising.