In this episode of the Happy Whole You podcast, Dr. Anna Marie Frank sits down with Dr. Edward Park, a Harvard- and Columbia-trained physician who spent 17 years in OBGYN before pivoting to anti-aging medicine and telomerase activation. Dr. Park now specializes in exosome therapy, having performed nearly 4,000 procedures across six states. Together they explore how exosomes, once dismissed as "cellular poop", are actually the primary way cells communicate and heal, how they compare to stem cells and PRP, and why this regenerative approach may be more accessible than you think. The conversation also covers telomere science, the future of longevity medicine, stem cell banking, and the surprising benefits of nasal exosome delivery for cognition, mood, and even autism.



Hear more about:

 * Telomeres and why they shorten with every cell division
 * How exosomes differ from stem cells and PRP
 * Dr. Park's 89-year-old mother's remarkable recovery story
 * Treating joint injuries: shoulder, knee, Achilles tendon
 * Nasal exosome delivery for cognition and mood
 * Exosomes for autism and neuroinflammation
 * Stem cell banking and cord blood preservation
 * Telomerase activation supplement (TA-65) and its effects
 * Exosome quality, brands, and what to look for
 * Cost of exosome treatments
 * The future of longevity: frequency healing and regenerative medicine
 * Why Western medicine misses root causes
 * FDA approval status of exosomes and informed consent



About Dr. Edward Park:

Dr. Edward Park, MD, MPH, is the Founder and Medical Director of Recharge Biomedical in Los Angeles, specializing in regenerative medicine, exosome therapy, telomere science, longevity, and evidence-based anti-aging care. With clinical training from Harvard and Columbia, over 16 years attending and speaking at A4M conferences, and 7 years of exosome experience, he has treated 709+ patients and performed 3,454+ procedures.



Get in touch with Dr. Edward:

drpark@rechargebiomedical.com

epark89@yahoo.com

(714) 369-8633

Youtube: @drpark65 [https://www.youtube.com/@drpark65]

Instagram: @dredpark [https://www.instagram.com/dredpark/]

Substack: @dredpark [https://substack.com/@dredpark]



Connect with Anna:

Email: annamarie@happywholeyou.com / info@HappyWholeYou.com

Website: www.happywholeyou.com [http://www.happywholeyou.com/] / https://linktr.ee/happywholeyou

Personal Website: www.DrAnnaMarie.com [http://www.drannamarie.com/]

Instagram: @happywholeyou [https://www.instagram.com/happywholeyou/]

Personal Instagram: @Dr.Anna.Marie

Facebook: Happy Whole You [https://www.facebook.com/happywholeyou]

LinkedIn: Anna Marie Frank [https://www.linkedin.com/in/annamariefrankhappywholeyou/]

Venmo: @happywholeyou [https://account.venmo.com/u/happywholeyou]

280. Slowing Aging: Exosomes, Telomeres & the Science of Living Longer with Dr. Edward Park

In this episode, Anna Marie sits down with performance coach Angie Wisdom to unpack why success often feels like it's shrinking your capacity instead of expanding it. Angie breaks down the three keys to reclaiming your mental bandwidth, protect, direct, and expand, and explains how emotional leaks, overthinking, and the drive to "get it right" are silently taxing your brain's resources. From the neuroscience of the prefrontal cortex to the body's physical warning signs, this conversation is a wake-up call for high achievers running on empty.



Hear more about:

 * Why success can actually shrink your capacity
 * The "open tabs" metaphor for mental overload
 * What What Got You Here Won't Get You There has to do with capacity
 * The iPhone low-battery analogy for a maxed-out brain
 * Protecting capacity from emotional and mental leaks
 * Why frustration, worry, and self-doubt are capacity thieves
 * Choosing whether to "allocate capacity" to a feeling
 * Directing capacity with intentionality and the money analogy
 * Expanding capacity through automation and habit
 * How identity and belief systems free up mental bandwidth
 * The default mode network and where your best ideas come from
 * Why wins stop feeling good when you're maxed out (dopamine vs. cortisol)
 * How the need to "get it right" steals joy and creativity
 * Physical signs your nervous system is under capacity stress
 * The "capacity tax", and going duty-free
 * Why even a billion-dollar CEO might have more capacity than a solopreneur
 * Angie's upcoming free event on the freedoms of success (link in her Instagram bio)



Where to find more from Angie:

Website: www.angiewisdom.com [http://www.angiewisdom.com]

IG: @angiewisdom_



Connect with Anna:

Email: annamarie@happywholeyou.com / info@HappyWholeYou.com

Website: www.happywholeyou.com [http://www.happywholeyou.com/] / https://linktr.ee/happywholeyou

Personal Website: www.DrAnnaMarie.com [http://www.drannamarie.com/]

Instagram: @happywholeyou [https://www.instagram.com/happywholeyou/]

Personal Instagram: @Dr.Anna.Marie

Facebook: Happy Whole You [https://www.facebook.com/happywholeyou]

LinkedIn: Anna Marie Frank [https://www.linkedin.com/in/annamariefrankhappywholeyou/]

Venmo: @happywholeyou [https://account.venmo.com/u/happywholeyou]

279. Are You at Capacity… or Is Something Stealing It? with Angie Wisdom

Dr.She joins the Happy Whole You podcast to break down NAD, why this critical coenzyme declines as we age, how it drives everything from fatigue to heart health, and why IV NAD infusions fail to raise levels (and may even be dangerous). The conversation covers the science of NAD precursors, the importance of testing before and after supplementation, and how proper dosing with oral NMN can genuinely optimize your NAD levels. Hear more about:

 * What NAD is and why it's a "central node of life"
 * When NAD levels start declining (earlier than you'd think)
 * Top health issues linked to low NAD — fatigue, brain fog, sleep, inflammation, heart failure, and infertility
 * Why IV NAD infusions don't work — molecule size, rapid degradation, and insufficient dosing
 * The fatal risks associated with NAD IV therapy
 * Why anxiety and unease can be triggered by NAD IV
 * How most oral NAD supplements are under-dosed
 * The importance of testing NAD levels before and after any intervention
 * Optimal NAD range (55–80 µM) and what levels bring noticeable benefits
 * High-dose niacin's hidden link to insomnia and toxic NAD levels
 * The NAD + SinoAid combo for allergy relief
 * Dr. Shi's NAD Optimization Essentials bundle and membership program



Get 15% off - Use code DrFrank at checkout!

Use link: https://www.jinfiniti.com/sp/partner-nad-membership-special-offer/?_ef_transaction_id=&oid=10&affid=110



Learn more about Dr.She: https://www.jinfiniti.com/about-us/



Connect with Dr. Jin-Xiong She:



Dr. Jin-Xiong She [https://www.jinfiniti.com/dr-jin-xiong-she/] received his college education in China and earned his PhD in France. After a brief postdoctoral stint at the University of Florida, he advanced rapidly to Full and Endowed Professor, Division Chief of Experimental Pathology, and Director of Research at UF's Diabetes Center. In 2002, he became the Georgia Research Alliance Eminent Scholar in Genomic Medicine at the Medical College of Georgia, founding the Center for Biotechnology and Genomic Medicine and directing multiple core research facilities.



Dr.She has authored over 400 peer-reviewed papers (H-index 76, 19,000+ citations), secured over $100 million in research grants, and mentored numerous students and faculty. Ranked among Georgia's top 20 medical researchers, he has served as President of both the Chinese Geneticists in America and the ADA council on Immunology, Transplantation, and Immunogenetics. A serial entrepreneur, he founded or co-founded multiple companies in the US and China, and currently leads Jinfiniti Precision Medicine to optimize healthspan through biomarker testing and precision nutraceuticals. More details can be found on his LinkedIn [https://www.linkedin.com/in/jin-xiong-she-phd-311b461a7/] and Google Scholar [https://scholar.google.com/citations?user=heGp6m4AAAAJ&hl=en] profiles.



Connect with Anna:

Email: annamarie@happywholeyou.com / info@HappyWholeYou.com

Website: www.happywholeyou.com [http://www.happywholeyou.com/] / https://linktr.ee/happywholeyou

Personal Website:

278. Why Your NAD IV Is Doing Nothing (And What Actually Works) with Dr. Jin-Xiong She

Christine, host of the Girl Out of Order podcast, joins The Happy Whole You podcast for a candid five-question conversation about what happens when the version of you that built your success no longer fits. They explore shedding old identities, the Wheel of Life as a diagnostic tool, the freedom of stopping the argument with reality, how to curate the roles and labels you carry, and how to tell a hard season apart from an identity you've genuinely outgrown. Christine also shares her own story of navigating infidelity in her marriage, growing up in a dysfunctional home, and signing a new book deal.



Hear more about:

 * Shedding the "good girl" identity from childhood
 * The Wheel of Life tool for finding what's missing
 * Stopping the argument with reality, "now what?"
 * Choosing who you bring to hard situations
 * "Who am I now?" and dancing with your roles
 * Ripping off labels that no longer fit
 * Fixed values vs. seasonal values (Tony Robbins' Date With Destiny)
 * Life rules: family first, always tell the truth, become the friend you want
 * Christine's new book deal announcement
 * The True Legacy Collective mastermind group



Connect with Anna:

Email: annamarie@happywholeyou.com / info@HappyWholeYou.com

Website: www.happywholeyou.com [http://www.happywholeyou.com/] / https://linktr.ee/happywholeyou

Personal Website: www.DrAnnaMarie.com [http://www.drannamarie.com/]

Instagram: @happywholeyou [https://www.instagram.com/happywholeyou/]

Personal Instagram: @Dr.Anna.Marie

Facebook: Happy Whole You [https://www.facebook.com/happywholeyou]

LinkedIn: Anna Marie Frank [https://www.linkedin.com/in/annamariefrankhappywholeyou/]

Venmo: @happywholeyou [https://account.venmo.com/u/happywholeyou]

277. Identity Redesign for Shifting Times with Christine Gale

Sara Banta returns to the Happy Whole You podcast to break down why so many high achievers are running on empty despite coffee, peptides, and willpower. The root cause isn't a lack of effort, it's depleted mitochondria. Sara explains how everyday toxins, chronic stress, and post-pandemic spike protein damage are crushing cellular energy, and why foundational supplements like iodine and methylene blue can take ATP production from 2 to 36, no shortcut required.



Hear more about:

 * Why 96% of Americans are iodine deficient and what it does to your cells
 * The "parking spot" analogy for how halogens replace iodine
 * How iodine turns the P53 gene back on post-pandemic
 * Methylene blue's role in ATP and brain function
 * Why copper deficiency blocks the final step of energy production
 * The thyroid–liver connection you can't ignore
 * Why caffeine is a "credit card" for energy
 * What GLP-1 weight loss is really doing to your body
 * Free body-temperature test for thyroid function
 * Sara's son's cancer recovery story through cell health



Connect with Sara Banta:

https://acceleratedhealthproducts.com/Happy



Connect with Anna:

Email: annamarie@happywholeyou.com / info@HappyWholeYou.com

Website: www.happywholeyou.com [http://www.happywholeyou.com/] / https://linktr.ee/happywholeyou

Personal Website: www.DrAnnaMarie.com [http://www.drannamarie.com/]

Instagram: @happywholeyou [https://www.instagram.com/happywholeyou/]

Personal Instagram: @Dr.Anna.Marie

Facebook: Happy Whole You [https://www.facebook.com/happywholeyou]

LinkedIn: Anna Marie Frank [https://www.linkedin.com/in/annamariefrankhappywholeyou/]

Venmo: @happywholeyou [https://account.venmo.com/u/happywholeyou]

276. Why You're Constantly Tired (And How to Fix It) | Methylene Blue & Iodine Secrets with Sara Banta

This episode features a live panel conversation with Dr. Monique Rogers, Courtney McDermott, and Dr. Anna Marie Frank, recorded at a women's community event in Bakersfield benefiting Casa Esperanza. The evening blends personal storytelling, practical wisdom, and raw honesty as three dynamic women unpack what it truly means to reclaim clarity, trust, and freedom. Topics range from the ego's role in protecting versus connecting, the neuroscience of the mind versus the brain, the art of asking unapologetically, navigating power dynamics in negotiations, healing from trauma, and the danger of competing instead of collaborating. The conversation is grounded in lived experience and offers both provocative insights and actionable tools for women ready to stop conforming and start leading with their soul.



"A desire ignored is a demon born. By not asking for what we need, we're creating our own internal chaos, and denying someone else the joy of giving." — Dr. Monique Rogers



Hear More About:

 * Ego as protector vs. soul as connector
 * What a dominatrix taught Dr. Monique about asking and receiving
 * Courtney's TEDx: the moment she tried to buy the TED stage
 * Why most people have no picture of their own mind
 * One question that instantly reclaims your agency in any room
 * Competition vs. collaboration — and how to rewire it
 * The micro-to-macro philosophy for inner and outer change
 * Happy Whole You: the wellness space that didn't exist 20 years ago



Connect with Anna:

Email: annamarie@happywholeyou.com / info@HappyWholeYou.com

Website: www.happywholeyou.com [http://www.happywholeyou.com/] / https://linktr.ee/happywholeyou

Personal Website: www.DrAnnaMarie.com [http://www.drannamarie.com/]

Instagram: @happywholeyou [https://www.instagram.com/happywholeyou/]

Personal Instagram: @Dr.Anna.Marie

Facebook: Happy Whole You [https://www.facebook.com/happywholeyou]

LinkedIn: Anna Marie Frank [https://www.linkedin.com/in/annamariefrankhappywholeyou/]

Venmo: @happywholeyou [https://account.venmo.com/u/happywholeyou]

275. Micro to the Macro (Live Panel)

In this conversation, Dr. Anna Marie and high-performance coach James Laughlin explore the shift from hustle culture to sustainable, habits-based high performance. They unpack how chasing external validation and constant achievement leads to burnout, nervous system dysregulation, and emptiness, and contrast that with a life built on clarity, boundaries, and aligned habits. James shares practical tools like micro "exposure therapy" to rest, leverage-based boundaries, and a simple daily journaling framework to help high achievers protect their health, redefine success from the inside out, and create impact without sacrificing well-being.



"If you don't make time for health, you'd better make time for sickness." – James Laughlin



Key Points:

 * Hustle feels great until it doesn't.
 * External validation (status, money, fame) is not sustainable fuel.
 * High performance = results and healthy relationships + well-being.
 * Signs of burnout: constant fatigue, flat mood, withdrawal, no joy.
 * Reducing work triggers fear; the brain reads "rest" as "danger."
 * Use small "exposures" to time off (e.g., 2 hours, then 4, then a full day).
 * Boundaries with yourself are harder than boundaries with others.
 * Leverage (painful consequence) helps you keep your own commitments.
 * Simple daily journaling: gratitude, what went well, what you learned, 1% better.
 * Top performers are radically clear on what success looks like for them.



Connect with Anna:

Email: annamarie@happywholeyou.com / info@HappyWholeYou.com

Website: www.happywholeyou.com [http://www.happywholeyou.com/] / https://linktr.ee/happywholeyou

Personal Website: www.DrAnnaMarie.com [http://www.drannamarie.com/]

Instagram: @happywholeyou [https://www.instagram.com/happywholeyou/]

Personal Instagram: @Dr.Anna.Marie

Facebook: Happy Whole You [https://www.facebook.com/happywholeyou]

LinkedIn: Anna Marie Frank [https://www.linkedin.com/in/annamariefrankhappywholeyou/]

Venmo: @happywholeyou [https://account.venmo.com/u/happywholeyou]

274. Habits of High Performers with James Laughlin

In this episode of the Happy Whole You Podcast, Dr. Robert Melillo returns to explore ADHD, brain development, and why so many modern mental health challenges may stem from brain imbalances rather than fixed "chemical defects." Looking through an evolutionary and developmental lens, he explains how reduced movement, increased technology use, and left-brain–heavy lifestyles are reshaping our brains. Together with host Dr. Anna Marie Frank, they unpack left vs. right brain dominance, ADHD subtypes, postpartum depression, and why focusing on our weaknesses, not just our strengths, may be the key to long-term brain and mental health.



"You're not broken. If anything, you are exceptional at something, and that gift is also what can leave you vulnerable." – Dr. Robert Melillo



Key points:

 * Movement is the foundation of brain development
 * Modern life (tech, sitting, toxins) is driving brain imbalances
 * Many issues (ADHD, autism, OCD, anxiety, depression) are developmental, not fixed defects
 * Our culture and schools overtrain the left brain and neglect the right brain
 * Right brain: social skills, emotional regulation, attachment, big-picture thinking
 * Left brain: data, goals, tech, ego, short-term focused attention
 * ADHD has different subtypes with different left/right brain patterns
 * True healing means strengthening weaknesses, not just doubling down on strengths
 * Medication can help short term, but long-term solutions focus on brain balance
 * The brain is highly plastic and can change at any age





About Dr. Robert Melillo:

Dr. Robert Melillo is a leading expert in developmental neurological conditions such as ADHD, autism, OCD, tics, dyslexia, anxiety, and depression in both children and adults. With extensive knowledge of brain function, he has perfected a noninvasive, multi-modal method to significantly improve and correct many neurological disorders. His expertise in functional neuroanatomy and neurophysiology is unparalleled, backed by 30 years as a clinician, professor, brain researcher, and bestselling author. His book Disconnected Kids, soon to release its 3rd edition, is a cornerstone in its genre, translated into 16 languages. Co-founder of Brain Balance Achievement Centers and developer of the Melillo Method®, he also runs the Melillo Center for Developing Minds in NY. Dr. Melillo directs the National Institute for Brain and Rehabilitation Sciences and co-hosts the web series Disconnected Kids Reconnected Families with his wife Carolyn, boasting over 3 million views. He also hosts The Melillo Method Podcast, Everything Brain.



Connect with Dr. Robert:

Email: drm@DrRobertMelillo.com

Website: DrRobertMelillo.com [http://drrobertmelillo.com/]

Phone: (516) 398-3454

LinkedIn: Robert Melillo [https://www.linkedin.com/in/robert-melillo-a287b618b/]

X: @DrRobMelillo [http://www.twitter.com/DrRobMelillo]

Facebook: Dr Robert Melillo [https://www.facebook.com/DrRobertMelillo/]

Instagram: @DrRobertMelillo [https://www.instagram.com/DrRobertMelillo/]

Youtube: Dr Robert Melillo [https://www.youtube.com/@drrobertmelillo]

Podcast: MelilloMethodPodcast,Everything Brain [https://podcasts.apple.com/ph/podcast/melillo-method-podcast-everything-brain/id1739403876]

Boo

273. Is ADHD a Sign of a Brain Imbalance? What Leaders Need to Understand Now with Dr. Robert Melillo

In this episode of the HAPPY WHOLE YOU PODCAST, Dr. Anna Marie Frank sits down with leadership and performance coach Sean Patton to explore the real difference between managing and leading, and why so many high achievers still end up feeling unfulfilled. Drawing from his military Special Forces background and his work with top performers, Sean shares how to move from task-focused management to true leadership that expands human capacity, aligns personal and business vision, and prevents leaders from hitting a silent ceiling of boredom and overwhelm. They dive into the inner work, the role of coaching, and the importance of listening to your body and intuition to stay in alignment with your highest, most authentic path.



"Leadership is about empowering and inspiring others to become a greater version of themselves than they ever thought was possible." – Sean Patton



5 Key Takeaways

 * True leadership starts with clarity of mission and communication, but in civilian life you must learn to define the mission from within, not just follow one handed to you.
 * Management maximizes the efficiency of existing systems, while leadership expands human capacity beyond what people believe they're capable of.
 * A simple diagnostic is to list your tasks: if you can't clearly see how you're increasing human capacity, you're probably managing more than leading.
 * High-level leaders often hit a hidden ceiling where they feel both overwhelmed and bored, signaling it's time for deeper inner work and a new, more aligned vision.
 * Coaches help uncover blind spots and misaligned goals so you don't have to "hit empty" at the top; early alignment between inner purpose and outer impact prevents midlife crises of success.



About Sean Patton:

Sean Patton is a former U.S. Army Special Forces Commander turned executive coach, author, and host of the No Limit Leadership podcast. A West Point graduate, Brazilian Jiu-Jitsu black belt, and Masters World Champion, Sean is an Executive Performance Coach at Novus Global, working with founders and senior leaders committed to becoming the leaders they are capable of becoming.



Connect with Sean:

Website: https://SeanPatton.me [https://seanpatton.me]

Coaching: https://Novus.Global/seanpatton [https://novus.global/seanpatton]

Book (A Warrior's Mindset: The 6 Keys to Greatness): https://www.amazon.com/Warriors-Mindset-Keys-Greatness/dp/B09HG54YS4

Podcast (No Limit Leadership): https://nolimitleadership.buzzsprout.com [https://nolimitleadership.buzzsprout.com/]

LinkedIn: https://www.linkedin.com/in/nolimitleadership [https://www.linkedin.com/in/nolimitleadership/]

Instagram: https://www.instagram.com/nolimitleadership [https://www.instagram.com/nolimitleadership/]

YouTube: https://www.youtube.com/@NoLimitLeadership

Social handle across all platforms: @NoLimitLeadership



Connect with Anna:

Email: annamarie@happywholeyou.com / info@HappyWholeYou.com

Website: www.happywholeyou.com [http://www.happywholeyou.com/] / https://linktr.ee/happywholeyou

Personal Website: www.DrAnnaMarie.com [http://www.drannamarie.com/]

Instagram: @happywholeyou [https://www.instagram.com/happywholeyou/]

272. From Bankrupted to Executive Millionaire with Sean Patton

You've probably heard about peptides for anti aging, weight loss, and recovery, but oral peptides bring a different angle. Instead of injections, you're looking at a simpler approach that still targets growth hormone support, tissue repair, and overall longevity. The key is not just taking them, but knowing which ones work, like MK-677 and BPC-157, and how they fit into your routine.

You also need to think about quality and safety. Sourcing from compliant pharmacies and following proper dosing matters more than hype. Microdosing, working with experienced practitioners, and understanding how your body responds can make the difference between real results and wasted effort.

This is not about chasing shortcuts. When you combine smart peptide use with solid habits like nutrition, recovery, and hormone balance, you give your body a better shot at long term performance and healthy aging.



In this Episode, You'll Learn:

 * Understanding Oral Peptides
 * Clinical Trials and Peptide Effectiveness
 * Natural Peptide Production and BHRT
 * Anti-Aging and Weight Loss with Peptides
 * Oral vs. Injectable Peptides
 * Microdosing and Peptide Dosage
 * Upcoming Event and Resources



About Dr. Nick Delgato:

Dr. Nick Delgado, PhD, is a leading anti-aging expert, author, researcher, and clinician whose work centers on longevity, hormone balance, and functional medicine. As the founder of the Delgado Protocol, he champions plant-based nutrition, stress reduction, and precisely targeted supplements to improve health span. With over 45 years in lifestyle medicine, Dr. Delgado has helped countless individuals achieve optimal health and vitality through seminars, webinars, and his expansive media presence. An acclaimed author of 15 books, including Stop Aging Now, he is widely regarded as a trusted advisor to physicians and patients alike, guiding audiences toward longer, stronger, and more purpose-driven lives.



Connect with Dr. Nick:

Instagram: https://www.instagram.com/dr.nickdelgado/

YouTube: https://www.youtube.com/DelgadoVideo

Delgado Protocol for Health Store: https://delgadoprotocol.com/

Forever Young Event Page: https://foreveryoungevent.com/

Estroblock Pro (Our Bestseller): https://www.amazon.com/Estroblock-PRO-TRIPLE-STRENGTH-3-Carbinol/dp/B00O2SZZ56?th=1

His Most Popular Talk: https://www.youtube.com/watch?v=2eNVN4Ui5GQ



Connect with Anna:

Email: annamarie@happywholeyou.com / info@HappyWholeYou.com

Website: www.happywholeyou.com [http://www.happywholeyou.com/] / https://linktr.ee/happywholeyou

Personal Website: www.DrAnnaMarie.com [http://www.drannamarie.com/]

Instagram: @happywholeyou [https://www.instagram.com/happywholeyou/]

Personal Instagram: @Dr.Anna.Marie

Facebook: Happy Whole You [https://www.facebook.com/happywholeyou]

LinkedIn: Anna Marie Frank [https://www.linkedin.com/in/annamariefrankhappywholeyou/]

Venmo:

271. Oral Peptides & Longevity with Dr. Nick Delgato

Better health, wealth, happiness, and success grows when your brain and biology thrive. Brain health and wellness enthusiast share the key biological downloads that have helped them and hurt them. Thi

Happy Whole You · Zencastr

Happy Whole You

Better health, wealth, happiness, and success grows when your brain and biology thrive. Brain health and wellness enthusiast share the key biological downloads that have helped them and hurt them. This podcast is for anyone looking to upgrade their brain, biology, and life! Get ready to hack into a new you!